例如,L-DOPA是帕金森病的主要治疗药物,能够提高多巴胺水平,缓解运动障碍症状。此外,多巴胺受体激动剂和拮抗剂等药物也被广泛应用于神经精神疾病的治疗。 结论:多巴胺作为一种重要的神经递质,对人体的生理和病理过程起着重要的调节作用。了解多巴胺的分子结构以及其功能与疾病关联对于深入理解神经递质的作用机制和药物研发...
Di Stefano, A
L-DOPA 100% Pure Levodopa Mucuna Pruriens Dopamine71 Reviews $19.95 Weight: * 10g 25g 50g 100g 250g 500g 1000g 2500g 5000g 10kg 25kg Current Stock: Quantity: Increase Quantity: Decrease Quantity: Share:Description Reviews Shipped and Made in the U.S. Derived from Mucuna Pruriens ...
英文名称：DSPE-PEG-L-DOPA，Phospholipids-PEG-L-DOPA，DSPE-PEG-L-DOPAmine，Phospholipids-PEG-L-DOPAmine 中文名称：二硬脂酰基磷脂酰乙醇胺聚乙二醇左旋多巴胺，二硬脂酰基磷脂酰乙醇胺PEG左旋多巴胺 一、结构特点 磷脂质（DSPE）：提供疏水性和与细胞膜相互作用的特性。聚乙二醇（PEG）：提供亲水性，改善血...
Furthermore, l-dopa dose-dependently increased intracellular reactive oxygen species (ROS) and cell death. Dopamine, ROS production and cell death were attenuated by co-incubation with the AADC inhibitor, NSD-1015. The MAO inhibitor, pargyline, also attenuated cell death and ROS after l-dopa ...
Levodopa (L-dopa) has proved valuable both as a therapeutic and research tool. Its therapeutic usefulness, as is well known, rests with its treatment of Parkinson's disease, and only recently has hope been kindled for its usefulness in t... Liskow,Barry,I. - 《Jama the Journal of the...
60年代，人们证实帕金森病是黑质致密区多巴胺能神经元变性所致，用多巴胺的前体左旋多巴(L-DOPA)可获较好疗效，这对多巴胺的研究起了极大的推动作用。70年代中，应用放射受体结合分析方法证实体内存在着多巴胺受体，某些化合物能与其结合而产生生理效应。进入80年代后，大量实验深入分析了DA受体的亚型及其与多种生理功能...
Larger doses of l-DOPA result in a shorter latency, higher incidence and higher severity of dyskinesia [10]. If the l-DOPA dose is sufficiently high and the nigrostriatal DA pathway is severely damaged, abnormal involuntary movements (AIMs) can also be elicited by acute treatment with l-DOPA...
Dopamine + Serotonin Booster* Mucuna, also known as velvet bean, is one of the only naturally occurring (and certainly most concentrated) sources of L-Dopa—as in dopamine. L-Dopa is a naturally occurring amino acid which transforms into dopamine