Gangreneof extremities has occurred when high doses were administered for prolonged periods or in patients with occlusivevasculardisease receiving low doses of dopamine hydrochloride This document does not contain all possible side effects and others may occur. Check with your physician for additional in...
Nayak, S., and Cassaday, H.J. (2003). The novel dopamine D4 receptor agonist (PD 168,077 maleate): doses with different effects on locomo- tor activity are without effect in classical conditioning. Prog. Neuropsy- chopharmacol. Biol. Psychiatry 27, 441-449....
The behavioral and neurochemical effects of SCH3390 (SCH), a dopamine (DA) D1 antagonist, and haloperidol (HAL), a DA D2 receptor antagonist, on schedule-induced polydipsia (SIP) were examined. Once animals were made polydipsic, a vehicle or one of three doses of SCH or HAL were admi...
Effects of subchronic amphetamine or amfonelic acid on rat brain dopaminergic and serotonergic function Repeated doses of direct or indirect CNS stimulants are known to cause behavioral hyper sensitivity. The biochemical basis for hypersensitization remains u... B.,A.,McMillen,... - 《Journal ...
To address the role of striatal dopamine in these effects, we compared the effects of the nonspecific catecholamine enhancer methylphenidate with those of the selective dopamine D2/3-receptor antagonist sulpiride. At low doses, sulpiride acts preferentially presynaptically to increase synaptic dopamine ...
This probably explains why, even at very high doses, DHX does not have amphetamine-like actions in vivo (Darney et al, 1991) as would be expected from a drug activating both D1 and D2 receptors. Moreover, the turning induced by DHX in unilateral 6-OHDA rats is completely blocked by ...
PET studies have shown that D2 occupancy is unlikely to be important with clinical doses of DHX (Slifstein et al, 2011), and because the improve both native processes and reverse scopolamine- a2-adrenergic affinity is five times lower than the D2, it induced deficits (Steele et al, 1997...
High (2.5–5 μg) doses of ventral tegmental morphine, which normally facilitate brain stimulation reward, were found to cause a complete cessation of bar ... PP Rompré,RA Wise - 《Brain Research》 被引量: 97发表: 1989年 Dopamine tone increases similarly during predictable and unpredictable ...
Intermediate doses of pimozide generally increased self-administration of cocaine or piribedil, though increases in piribedil self-administration were more reliable. In contrast, intermediate doses of SCH 23390 either did not affect or decreased cocaine and piribedil self-administration. High doses of ...
**po0.001 in the comparison between the raclopride-treated mice (at all three doses) and the saline-treated group. significant effect of DEM food (F(1, 23) ¼ 3.92, po0.050). Thus, while raclopride at all doses did not affect social learning, merely receiving a saline injection ...