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Here we present a new crystal structure of SOS that contains the N-terminal histone domain in addition to the DH-PH unit and the catalytic unit (SOSHDFC, residues 1-1049). The structure reveals that the histone domain plays a dual role in occluding the allosteric site and in stabilizing ...
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chimeras in which As expected, when the entire C1 domain of STAC3 was replaced (STAC3-C1-GFP), the chimera lost its ability to colocalize in clus- t(eSrTsAwCi3th-CC1a-VB1-.G2 F(P0.)0a ±m 0in.0o%a)c.idInstweriethsttihnogslye, 0 ± 0.0%). This ...
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