DBM has been clinically used since the beginning of the 1980s [15], but evidence for or against its ability to form new bone is still poor as osteogenic activity is age- and gender-related, and depends on the lifestyle habits (drinking alcohol, smoking habit, etc.) of both the donors ...
Although, e.g., IEA TCP activities have significant contributions here (see Section 2.2), there is also still a lot to accomplish. Long-term stability of PCMs is one such key parameter with not enough attention and standardization yet. In IEA SHC/ECES Task 58/Annex 33 [22], to test ...