MARK4, belongs to AMP-activated protein kinases (AMPKs) subfamily of calcium/calmodulin dependent protein kinases (CAMK). It plays a central role in regulation of cell shape and polarity during differentiation, chromosome partition in mitosis, and intracellular transport by acting on microtubule-associ...
The 1α-hydroxylase is regulated, in part, by parathyroid Hormone (PTH), serum phosphate, calcium and the Fibroblast Growth Factor-23 (FGF-23) [13, 14]. PTH and hypophosphatemia stimulate the action of this enzyme, whereas hypercalcemia and FGF-23 repress it [15]. In contrast to 1α-...
In this study, three approaches were taken to specifically address whether BMAT adipocytes have the potential for UCP1 expression: 1) immunohistochemical detection of UCP1 protein in intact tissue, 2)Ucp1-Cre-driven and DTA-mediated cell ablation, and 3)Ucp1-Cre-mediated lineage tracing. Immunohi...
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