1 showed that prior tuberculin skin tests (TST) do not induce false-positive QuantiFERON-TB Gold in-tube (QFT-GIT) assay results when evaluated in the days immediately following TST administration. In the same issue of the ERJ , Naseer et al. 2 reported the results of a study of 10 ...
In order to exclude active TB, microbiological standard analysis was performed. A diagnosis of LTBI was based on a positive QFT-IT test in conjunction with no radiological finding suggestive of active TB and negative microbiological assay. For cases of LTBI, a standard prophylactic treatment with ...
Therefore, we conclude that the criterion of 5 mm TST reaction defining latent TB infection in our population should be re-evaluated. It may be more appropriate to substitute the traditional TST for newer diagnostic tools as the QuantiFERON assay. Larger studies are needed to verify our results...