Poly(A)-containing mRNA has been complexed with poly(U) to form mRNA:poly(U) 2 and reisolated by hydroxyapatite chromatography. This preparation stimulates both the incorporation into protein of 3H-leucine and 35S-methionine from F-met-tRNA f equally well, as does normal mRNA. We conclude th...
Translation is the final step of translating a DNA sequence into a functional protein. RNA/protein complex molecules called "ribosomes" attach themselves to the modified mRNA strand and translate the strand into a chain of protein molecules. This is accomplished by transfer RNA (tRNA) molecules th...
To make a structural or functional protein, a cell needs to get genetic information from DNA out of the nucleus and into the rest of the cell, where the protein-producing machinery is located. Nucleic acids called mRNA, for messenger ribonucleic acid, form in the nucleus. They copy informatio...
ion tra Previous work by Namy and colleagues23notably identified eight genes inS.cerevisiaeto have enhanced read-through properties (>10-fold stop codon bypass efficiency) compared to mRNA levels. However, they found that only two of those genes,IMP3andBSC4, displayed increased read-through in a...
President Coolidge’s statement, “The business of America is business,” still points to an important truth today—that business institutions have more prestige（威望）in American society than any other kind...
tRNA Ligase Is Required for Regulated mRNA Splicing in the Unfolded Protein Response. Cell 1996, 87, 405–413. [CrossRef] 15. Sidrauski, C.; Walter, P. The Transmembrane Kinase Ire1p Is a Site-Specific Endonuclease That Initiates mRNA Splicing in the Unfolded Protein Response. Cell 1997, ...