Disclosures Off Label Use: azacitidine: off-label use as maintenance therapy following allogeneic stem cell transplant for MDS/AML. Champlin:Otsuka: Research Funding. De Lima:Celgene: Research Funding.doi:10.1182/blood.V120.21.4209.4209Hans C. Lee...
In conclusion, lenalidomide treatment does not increase AML progression risk, but instead confers a possible survival benefit in RBC transfusion-dependent patients with del(5q) Low- or Int-1-risk MDS. 展开 关键词: Myelodysplastic syndromes acute myeloid leukemia progression survival lenalidomide del(5...
41 The precise role of RAS gene mutation in the pathogenesis of AML (or MDS) is yet to be defined. Clonogenic assays have identified a varying proportion of NRAS mutant and nonmutant colonies grown from AML bone marrow progenitors.28 That NRAS gene mutation was found in only more mature ...
Lenalidomide does not increase AML progression risk in RBC transfusion-dependent patients with Low- or Intermediate-1-risk MDS with del(5q): a comparative analysis. Leukemia 2013; 27: 1072-79.Kuendgen A, Lauseker M, List AF, et al. Lenalidomide does not in- crease AML progression risk in...
D. Reis, et al., "Iron overload and haematopoiesis in MDS: does blood transfusion promote progression to AML?" Blood, vol. 112, no. 11, p. 928a, 2008.Chan L, Buckstein R, Reis M, Chesney A, Lam A, Cheung M, Piliots E, Gu L, Wells R (2009) Iron overload and haematopoiesis...
Busulfan Does Intensity and Outcomes in Reduced Intensity Allogeneic Stem Cell Transplantation for MDS/AMLdoi:10.1016/j.bbmt.2012.11.037Yi-Bin ChenErin CoughlinCorey CutlerKevin KennedyEdwin P. Alyea IIIPhilippe ArmandEyal C. AttarKaren Ballen
Real-World Azacitidine use does not Replicate AZA-001 Results in Higher-Risk MDS/Low-Blast Count AML: Audit of 1101 Patients in Ontario, CanadaOverexpression of the histone methyltransferase MMSET in t(4;14)+ multiple myeloma patients is believed to be the driving factor in the pathogenesis of...
AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis. Cell 1996, 84, 321–330. [Google Scholar] [CrossRef] [Green Version] Wittamer, V.; Bertrand, J.Y. Yolk sac hematopoiesis: Does it contribute to the adult ...
("an interdisciplinary cooperation of biology and technology or other fields of innovation with the goal of solving practical problems through the function analysis of biological systems, their abstraction into models, and the transfer into and application of these models to the solution"), bionics (...