Also known as biologic therapy, immunotherapy involves using the immune system to fight cancers. Examples include Colony-stimulating factors Interferon Interleukin Monoclonal antibodies Patients with advanced prostate cancer may decide to stop the medications because of the severe side effects that come wi...
Unconventional T Cells (UTCs) are a unique population of immune cells that links innate and adaptive immunity. Following activation, UTCs contribute to a host of immunological activities, rapidly responding to microbial and viral infections and playing key roles in tumor suppression. Aging and chroni...
The researchers increased the number of metal-binding sites per antibody to decrease the amount of immunoconjugate, in mg, required to deliver a therapeutic dose of radiometal. Furthermore, the low amount of injected tracer (picomoles to nanomoles, sum of radioactive, and stable molecules) enab...
Immunotherapy:Stem cells can play a role in modulating the immune system, making them valuable in treating autoimmune diseases and preventing transplant rejection. Mesenchymal stem cells, in particular, have demonstrated immune-modulatory and anti-inflammatory properties, which can be harnessed for therapeu...
In all three cases the latest metastases displayed an overall reduced level of HLA gene transcription. Even though the differences were not statistically significant (p=0.2), the tendency of HLA downregulation is apparent. This gradual decrease of HLA class I gene transcription appeared to be ...
Immunotherapy:Immunotherapy modulated the body’s immune system to help fight cancer. Targeted drug therapy:Targeted drug treatments target specific abnormalities present within cancer cells and block the abnormalities causing cancer cells to die.
The main treatments for non-Hodgkin lymphoma are: Chemotherapy, which uses drugs to kill cancer cells Radiation therapy, which uses high-energy rays to destroy cancer cells Immunotherapy, which uses your body's immune system to attack cancer cells Targeted therapy, which targets aspects of lymphoma...
Relationship to clinical severity and the results of immunotherapy. J. Clin. Invest. 52, 472–482 (1973). Article CAS PubMed PubMed Central Google Scholar Johansson, S. G. IgE in allergic diseases. Proc. R. Soc. Med. 62, 975–976 (1969). CAS PubMed PubMed Central Google Scholar ...
Blocking the PD-1 signaling pathway may be a new direction of immunosuppressive therapy of sepsis. This article will summarize the role of the PD-1 signaling pathway in sepsis and provide a new treatment direction for the immunotherapy of sepsis....
In biochemical, histological and immunochemical analysis, almost all inhibitors demonstrated dose-dependent or independent decrease in hyperphosphorylation of tau at sites that were specific for the inhibited kinases, which is indicative of the pharmacodynamic action of these inhibitors directly on tau. For...