There appears to be a broad consensus that estrogen is a cause of breast cancer. Proof of cause and effect in clinical medicine requires a different approach for an epidemiological exposure (a 'mosaic' approach) than for an infectious agent suspected of causing a particular disease (a 'chain ...
Does vaginal estrogen therapy increase risk of breast cancer in postmenopausal women? doi:10.1097/EBP.0000000000002260Wolters KluwerEvidence-Based PracticeJoseph A. SimmermanJoel Herness
ESR1 single nucleotide polymorphisms predict breast cancer susceptibility in the central European Caucasian population. Estrogen and progesterone hormones are key regulators of a wide variety of biological processes. In addition to their influence on reproduction, cell diffe... MF Lipphardt,M Deryal,FO...
Breast cancer is a variant of cancer that is very sensitive to high levels of estrogen. Those who had ovarian cancer before are at an increased risk of having the cancer. Answer and Explanation:1 Breast cancer is capable of metastasizing to the lungs. In fact, it has a high chance of do...
microRNAs (miRNA) have emerged as a major player in gene regulation, thus identification of miRNAs associated with normal or disrupted estrogen signaling is critical to enhancing our understanding of the diagnosis and prognosis of breast cancer. We have previously shown that 17β-estradiol (E2) ...
Endometriosis is a chronic, estrogen-dependent, benign condition, affecting 10–15% of women of reproductive age. It is associated with a prevalence of sexual dysfunction that is nearly twice as high as that seen in women with other benign gynecological conditions. Our study aimed to assess the...
A group of estrogen-blocking breast cancer drugs called aromatase inhibitors (anastrozole, exemestane, letrozole) may make your bones more brittle. That may cause bone and joint pain. Certain types of chemotherapy can also cause bone thinning. If you aren’t already inmenopause, it may start pre...
New evidence shows that extended estrogen suppression treatment using aromatase inhibitors for hormone receptor-positive postmenopausal breast cancer is safe; it does not increase the risk of coronary artery calcification, a sign of active coronary ather
Combination treatment also reduced the number of estrogen receptor–positive cells in treated tumors. Another study in C3H/OuJ mice, which spontaneously develop mammary tumors, found similar beneficial interactions between green tea and tamoxifen (57). Whereas treatment with green tea extract (1%) as...
Trials have shown that the growth of estrogen-dependent and HER2+ breast cancer cells is inhibited by the effects of Afinitor. Combination treatment with other agents such as exemestane (Aromasin) for breast cancer enhances its effects. What is Afinitor used to treat?