1 It is quite possible that, as more patients survive the initial insult as a result of advances in ECMO circuit designs, centrifugal pumps, as well as improved pharmacologic management, overall CAV incidence will increase over time. The adverse impact of donor ischemic time on higher PGD rates...
Nevertheless, these data suggest that hyperventilation- induced hypocarbia may have less impact on metabolic rate in newborns than has been reported to occur in mature humans and animals. REFERENCES 1. Fox WW, Duara S 1983 Persistent pulmonary hypertension in the neonate: diagnosis and management. ...
There are also concerns regarding excessive exposure to NH since it can result in atelectasis and pulmonary injury, increased oxidative stress and potential harm in critically ill patients. In this context a further preliminary study of the impact of NH on the injured brain was warranted. ...
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It is important to note that VGLUT2 might have a role in unconscious proprioception as well, since diffuse TBI induces the susceptibility of Purkinje cells due to long-range neuronal circuit disruption [65]. It is noticeable as a consequence that VGLUT2 synaptic density is substantially reduced ...
Other oxadiazoles were shown to be more efficient than PTC124 in a Fisher rat thyroid (FRT) cell model [302,303], but for now, none have yet reached clinical testing. Novel, synthetic aminoglycosides, such as NB54 and NB124 (ELX-02), had a more favorable toxicity and bio-availability...
Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression. Gut 2005, 54, 1391–1395. [CrossRef] [PubMed] 64. Nicolas, G.; Chauvet, C.; Viatte, L.; Danan, J.L.; Bigard, X.; Devaux, I.; Beaumont, C.; Kahn, A....