The wound-healing assay was used to dectect the effect of DOCK9-AS2 on the migration of the BCPAP cells. Results The expression of DOCK9-AS2 in PTC tissues (0.0097卤0.0044) was significantly higher than that of adjacent tissues (0.0026卤0.0010) (P<0.05). The expression...
Functionally, DOCK9-AS2 knockdown reduced proliferation, migration, invasion, epithelial-to-mesenchymal (EMT) and stemness in PTC cells. PTC-CSCs transmitted exosomal DOCK9-AS2 to improve stemness of PTC cells. Mechanistically, DOCK9-AS2 interacted with SP1 to induce catenin beta 1 (CTNNB1) ...