Print datasheet MSDS Cat No.18987-1-AP Freight/Packing:-- Country/Region Please contact our China branch Proteintech Guarantee Request bulk or custom quote Background Information DOCK9 is a guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Its ...
产品名称: DOCK9蛋白抗体 英文名称:DOCK9 别名:Cdc42 guanine nucleotide exchange factor zizimin 1; Dedicator of cytokinesis protein 9; DKFZp686C11110; DKFZp686D2047; DKFZp686N04132; DOCK 9; FLJ16744; FL
Cell division control protein 42 homolog (Cdc42) influences a variety of cellular responses such as cell migration and polarity. Deregulation of Cdc42 has been associated with several human diseases and developmental disorders. Over‐activation of Cdc42 through guanine nucleotide exchange factor (GEF)...
Cdc42 guanine nucleotideAnti-DOCK9抗体exchange factor zizimin 1; Dedicator of cytokinesis protein 9; DKFZp686C11110; DKFZp686D2047; DKFZp686N04132; DOCK 9; FLJ16744; FLJ44528; DOCK9_HUMAN; FLJ45282; FLJ45601; KIAA1058; KIAA1085; ZIZ1; Zizimin1. ...
背景介绍:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation。 图像: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab02499 (DOCK9 Antibody) at dilution of 1:200。
Biochemistry Atypical guanine nucleotide exchange factors for Rho family GTPases| DOCK9 activation of Cdc42 and SmgGDS activation of RhoA THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL John Sondek HamelBrant LRho GTPases regulate diverse cellular processes ranging from cell morphology and motility ...
Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleo- tide exchange factors. J Biol Chem 2008; 283:3088- 96; PMID:18056264; http://dx.doi.org/10.1074/jbc. M705170200.Kwofie MA, Skowronski J. Specific Recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 Guanine ...
Compound docking to Cdc42 based on DOCK9 magnesium exclusion model.Tudor I., OpreaLarry A., SklarJacob O., AgolaYuna, GuoMelina, SilberbergJoshua, RoxbyAnna, VestlingElsa, RomeroZurab, SurviladzeCristina, MurrayKrezan
Here, we describe a C-terminal DOCK9 fragment, soluble in bacteria, that is sufficient to catalyze nucleotide exchange on Cdc42. We also provide evidence that full-length DOCK9 is significantly more active than the minimal GEF domain, implicating the ability of other domains to contribute to ...
(2009) Regulation of dendrite growth by the Cdc42 activator Zizimin1/Dock9 in hippocampal neurons. J. Neurosci. Res. 87, 1794 -1805Kuramoto, K., Negishi, M., Katoh, H., 2009. Regulation of dendrite growth by the Cdc42 activator Zizimin1/Dock9 in hippocampal neurons. J Neurosci Res ...