Statins are some of the most popularly prescribed medications on the market with1 in 4 Americans taking statin drugs (2011). Do they work? To read the read theearly reports statins were wonder drugs, capable ofreducing heart attackandextending lifespanwith fewside effects. No need to change o...
IMNM is characterized by: proximal muscle weakness and elevated serum creatine kinase that persists despite discontinuation of statin treatment; positive anti-HMG-CoA reductase antibody; muscle biopsy showing necrotizing myopathy; and improvement with immunosuppressive agents. Additional neuromuscular and ...
A gap exists between guidelines and real-world clinical practice for the management and treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in the last decade, there is room for improvement in detection rates, treatment
Statin medications do come with their risks. The most prominent ones are muscle pains, weakness, and fatigue, however,the worst possible muscle side effect is rhabdomyolysis (the breakdown of muscle tissue). The next most common complaints are cognitive in that they feel that their brain functio...
Fruiting bodies and mycelium extracts of edible mushrooms (some more than others) can be a valuable source of lovastatin, which is a statin group compound [76]. This compound inhibits HMG-CoA reductase, which is the rate-limiting step in cholesterol biosynthesis. Thus, MMs with activity associat...
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fects to be homogeneous in magnitude for all drugs from a common class by forcing a constant response percen- tile for each class based on the response percentile of the first drug in each class, which was determined ran- domly. We ran data for patients through the simulation ...