Statins are a group of medications that lower a specific type of cholesterol level in your blood. The best alternatives to statins are PCSK9 inhibitors, fibric acid derivatives or fibrates, bile acid sequestrants, selective absorption inhibitors, nicotinic acid or niacin, and omega-3 fatty acids ...
The size of apolipoprotein (a) is an independent determinant of the reduction in lipoprotein (a) induced by PCSK9 inhibitors Cardiovasc. Res., 118 (9) (2022), pp. 2103-2111 CrossrefView in ScopusGoogle Scholar [6] G. Reyes-Soffer, H.N. Ginsberg, L. Berglund, P.B. Duell, S.P. ...
3.4. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK-9) Inhibitors PCSK-9 is another relevant cholesterol-lowering target that is involved in the regulation of LDL receptors. The gene that encodes PCSK-9 is implicated in familial hypercholesterolemia, and their gain- and loss-of-function mutati...