As genetic factors, MHC class II gene polymorphisms have been shown to contribute most strongly to susceptibility to type 1 diabetes, and disease susceptibility haplotypes for each race have also been identified.doi:10.1111/jdi.13155Hiroyuki Sano...
Where are helper T-cells found? What are some of the actions of helper T cells? Are helper T-cells specific for an antigen? Which cells activate helper T-cells by antigen presentation? Can B cells be activated without T cells? Do helper T-cells have MHC type 2?
Red blood cells do not contain mitochondria, so how do red blood cells generate most of their ATP? How do cells perform Pinocytosis and drink blood from capillaries? How is carbon dioxide transported in the blood? Why don't red blood cells have MHC1?
Why do red blood cells use glucose as an energy source? In cellular respiration, ___ ATP molecules must be input to initiate the process of glycolysis. A) 2 B) 3 C) 5 D)6 Do red blood cells have ribosomes? If a yeast cell were to lose its mitochondria, would it still be able ...
Antigen Recognition: T cells recognize antigens presented by antigen-presenting cells (APCs), such as dendritic cells, that have captured and processed pathogens or foreign substances. The antigen is usually presented on the major histocompatibility complex class II (MHC-II) molecules. ...
HLA-DO has been described as a natural inhibitor of HLA-DM, and its expression has been mainly confined to B cells, mature DCs, and thymic epithelial cells. We therefore investigated whether expression of HLA-DO could restore presentation of DM-sensitive antigens in HLA-DM–positive cells. We...
They have been proposed as species within the MCVs genus [11, 30, 32]. Megalocytiviruses provoke systemic, often life-threatening diseases, characterised by enlarged cells called ‘inclusion body-bearing cells’ in infected organs and tissues such as the spleen, kidney, gastrointestinal tract, ...
A second non-classical MHC-II molecule, HLA-DO (DO), is an inhibitor of DM function and is expressed in a subset of DM-expressing APC types, specifically B cells, some types of dendritic cells (DC) and thymic medullary epithelia9–11. The crystal structures of DM-DO and DM-MHC-II ...
Gu et al. suggest that if DO is acting by inhibiting DM that inhibition should be spatially or temporally regulated to result in a qualitatively different spectrum of peptides presented on MHC-II [37••], as has been reported in class II peptide elution studies of B cells with and wit...
Why don't red blood cells have MHC1? When stained with Wright's stain basophil cells do what? Why it is beneficial for cells to be small? Why do B-cells need helper T-cells? Why are animal cells more irregularly shaped than plant cells?