Chapter 14/ Lesson 8 17K As an inherited disorder commonly found in individuals of African descent, sickle cell anemia affects red blood cells, making them abnormally sickle-shaped, which results in a blockage of blood flow. Learn more about sickle cell anemia, including the affected locations of...
Molecular subgroups of T-cell acute lymphoblastic leukemia in adults treated according to pediatric-based GMALL protocols Article Open access 14 May 2024 Allogeneic hematopoietic stem cell transplantation overcome the poor prognosis of patients with IKZF1plus CD20–a very high-risk subtype in B-cell...
cell-based treatments. They carry a patient’s own DNA, and their versatility makes them similar to embryonic stem cells, only they are reprogrammed from adults’ skin or blood cells.
You may have noticed that this section of my reviews has been neglected for a while now.That’s because there hasn’t been anything worth quoting.But somehow, this time around, there was so much great dialogue I had to pick and choose and still left some great quotes out. Scully and Mu...
How do high-dose therapy plus autologous stem cell transplantation compare with chemotherapy or immunochemotherapy in adults with follicular lymphoma?doi:10.1002/cca.437Sera TortChantal CassisJohn Wiley & Sons, Ltd
have allowed analyzing the mechanisms of MPSII pathogenesis in female carriers. The resulted iPSCs demonstrated characteristic pluripotency markers, deficiency of theenzymeactivity, and mutation in theIDSgene. These cells have been capable of differentiation into cardiomyocytes and neurons. In MPSII-iPS...
Among the innate immune cells, microglia are the primary players in neuroinflammation. Activated microglia exhibit diverse phenotypes and have multifaceted interactions with amyloid-β and tau species as well as with neuronal circuits. Activated microglia might have diverse influences on the progression of...
Hegazy, Pascal Gélébart, Jianchang Yang, Yupo Ma, Raymond Lai Expansion of hematopoietic stem cells for transplantation: current perspectives Jessica A. Schuster, Maria R Stupnikov, Gina Ma, Wenbin Liao, Raymond Lai, Yupo Ma, Jerell R Aguila Blockade of fatty acid synthase triggers ...
FSH-induced Akt phosphorylation is inhibited in rat granulosa cells treated with a covalent inhibitor of IGF1R (NVP-AEW541)43, leading to a decreased expression of genes involved in the germline proliferation. Consistent with this evidence, in the male gonad, the IGF system appears to have an ...
To determine the influence of B-cell numbers on the VH6 repertoire posttransplant, IgM VH6 H CDR3 fingerprinting profiles of 3 normal adults and 3 stem cell recipients were compared in a limiting dilution analysis using equal numbers of B cells. Samples from patients no. 1, 9, and 11 obt...