Lipoprotein lipase (LPL), located at the vascular endothelium, catalyzes the hydrolysis of plasma triacylglycerols to fatty acids and 2-monoacylglycerol. In the heart, LPL is synthesized in cardiac myocytes and then translocated to the vascular endothelium. We investigated whether lipolytic products co...
Differential effects of cis and trans fatty acids on insulin release from isolated mouse islets Differential ef- fects of cis and trans fatty acids on insulin release from isolated mouse islets of Langerhans. Diabetologia. 39:A113.Alstrup KK, ... KK Alstrup,S Gregersen,HM Jensen,... - 《Me...
(n-3) fatty acids reduce the release of prostaglandin E2 from bone but do not affect bone mass in obese (fa/fa) and lean Zucker rats. J Nutr 135(3): 499-504.Mollard RC, Gillam MET, Wood M, Taylor CG, Weiler. HA (2005). (n-3) Fatty acids reduce the release of prostaglandin ...
• Antacids may be used while taking naproxen and esomeprazole magnesium delayed-release tablets. 2.2 Recommended Dosage The recommended dosage of naproxen and esomeprazole magnesium delayed-release tablets by indication is shown in the table: Indication Patient Population Recommended Dosage Rheumatoid ...
CC Leslie - 《Prostaglandins Leukotrienes & Essential Fatty Acids》 被引量: 288发表: 2004年 cPLA2 phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells Cytosolic phospholipase A 2 (cPLA 2 ) is activated by phosphorylation at serine-...
Journal:Nucleic Acids Res PubMed ID:22879381 'Combinatorial interactions of transcription modulators are critical to regulate cell-specific expression and to drive direct cell reprogramming (e.g. trans-differentiation). However, the identification of key transcription modulators from myriad of candidate gen...
DegQ is about 455 amino acids long and shares 60% sequence homology with DegP. It is capable of rescuing temperature sensitive DegP− strain [25]. Like DegP−, it has two PDZ domains and cleaves its misfolded protein substrates and thereby, is capable of functionally complementing DegP ...
The bioavailability of olmesartan was not significantly altered by the co-administration of antacids [Al(OH)3/Mg(OH)2]. Olmesartan medoxomil is not metabolized by the cytochrome P450 system and has no effects on P450 enzymes; thus, interactions with drugs that inhibit, induce, or are metabolize...
Cooperativity decreased with free fatty acids in the order OA < EP0041 ≈ DHA. ΔH variations (Fig. 2c) also indicate that less heat was necessary to obtain the (Pβ’)-to-liquid crystalline (Lα) phase transition in the presence of polyunsaturated fatty acids, in agreement ...
about 40 μM25, (ii) has 15 lysines (Lys) in its sequence of 140 amino acids and (iii) is natively unfolded26, suggest that aS may be a target for DOPAL among synaptic proteins27. Concurrently, it was shown that DOPAL can cause aS oligomerization in vitro and in cell models4...