两种关键信号转导通路活性状态与K562细胞对DNR、Ara-C敏感性的关系
Ara-C疗效急性白血病诱导缓解化疗期最常见的并发症是感染,其次是出血,两者互相影响,常因此使化疗受挫,诱导缓解失败,甚至使患者致命.为了研究在既无隔离监护病室,又缺无菌空气层流病房的设备,在一般病室常规条件下,创造较好地净化病人内,外小环境,预防各种感染的简便有效的措施,应用常规全量有效化疗...
We investigated the in vitro induction of apoptosis by ARA-C, FLU (Fludarabine), VP-16, MITOX, DNR and IDA (Idarubicin) in the blast cells of 23 adult patients with untreated acute myeloid leukemia (2 M0, 2 Ml, 10 M2, 2 M4,4 M5,2 M6 and 1 M7). Mononuclear cells from the bone...
Induction of Apoptosis in Vitro by ARA-C, VP-16, MITOX, DNR, IDA and FLU in Myeloid Leukemic CellsNo AbstractMestice, A.Coppi, M. R.Specchia, G.Palumbo, G.Mininni, D.De Paolis, M. R.Quarta, A.Curci, P.Rossi, D.Vaira, A....