但绝大部分国内获证的产品还是检测HPV DNA,其中郑州科蒂亚生物技术有限公司的产品才检测HPV E6/E7 mRNA,使用的是支链DNA信号扩增法,该方法无需RNA抽提纯化、反转录和扩增等步骤,只需将样本裂解后,经探针杂交与信号放大即可获得基因检测结果。 二、HBV RNA检测 乙型肝炎病毒(Hepatitis B virus, HBV)是一种长度约为...
Everything that has been said here doesn’t just apply to humans. Other organisms, includingbacteriaand viruses, also haveDNAand/orRNA.The recent COVID-19 vaccines actually usemRNAfrom the virus itself in a rather sneaky way. Usually, a vaccine uses a weakened or damaged version of a virus...
This article introduces the regulatory role of m6 A in stem cell pluripotency and differentiation, virus infection and self-replication, and fruit fly sex determination. Meanwhile, the role of RNA modification in the regulation of other life processes is being revealed constantly, indicating that the...
花椰菜花叶病毒(Cauliflower Mosaic Virus,CaMV)是花椰菜病毒家族(卡利莫病毒/Caulimovirus)的成员,是感染植物的拟逆转录病毒。拟逆转录病毒像逆转录病毒一样通过逆转录复制,但病毒颗粒含有DNA而不是RNA。 病毒宿主 CaMV主要感染十字花科植物(如花椰菜和萝卜),但一些CaMV毒株(D4和W260)也能够感染曼陀罗和烟草属的...
图10. NadPrep® RNA & DNA tNGS 全流程解决方案对真实样本的检测表现。A. 文库产出;B. Rhinovirus A 和 Rhinovirus C reads 占比。 05 总结 随着NadPrep® RNA & DNA 共建库模块的正式推出,结合高效精简的 NEX-t Panel v1.0,快速稳定的 NadPrep®️ ES Hybrid Capture Reagents,以及可视化生信分析...
“HPV”众所周知,人乳头瘤病毒(human papilloma virus)单词首字母缩写,那么核酸检测是什么?其实大家应该也不陌生…… “今天你捅喉咙了吗?” “今天你做核酸了吗?” “大白喊你下楼做核酸喽!” 那么HPV核酸检测到底是怎么回事?今天我们来扒一扒! 核酸是脱氧核糖核酸(...
图10. NadPrep® RNA & DNA tNGS 全流程解决方案对真实样本的检测表现。A. 文库产出;B. Rhinovirus A 和 Rhinovirus C reads 占比。 05 总结 随着NadPrep® RNA & DNA 共建库模块的正式推出,结合高效精简的 NEX-t Panel v1.0,快速稳定的 NadPrep®️ ES Hybrid Capture Reagents,以及可视化生信分析...
DNA-PK deficiency restricts the replication of vesicular stomatitis virus (VSV) and HSV-1 To screen for compounds with antiviral activity, we treated THP-1 cells with a library of compounds and then infected them with a prototype RNA virus VSV carrying a luciferase reporter. As a positive con...
图10. NadPrep®RNA & DNA tNGS全流程解决方案对真实样本的检测表现。A.文库产出;B.Rhinovirus A和Rhinovirus C reads占比。 05总结 随着NadPrep®RNA & DNA共建库模块的正式推出,结合高效精简的NEX-t Panel v1.0,快速稳定的NadPrep®️ES Hybrid Capture Reagents,以及可视化生信分析平台和自动化解读报告...
We encountered several novel forms of viral mRNA: two distinctive src mRNAs in the same clone of cells; an env RNA appreciably larger than usual; and two mRNAs that appear to be encoded by the extreme right-hand end of the ASV provirus and adjacent cellular DNA. The first of these ...