Transcription factor 1 (TF1) is the Bacillus subtilis phage SPO1-encoded member of the family of DNA-binding proteins that includes Escherichia coli HU and integration host factor, IHF. A gel electrophoretic retardation method has been used to show that a TF1 dimer binding to one of its ...
We review and discuss the biological and DNA-binding properties of the bacteriophage SPOT transcription factor 1(TF1), a DNA-binding protein belonging to the ubiquitous prokaryotic family of Type II DNA-binding proteins. We review recent information on the effects of certain mutations in TF1 on DN...
b For each TF-pair, the proportion of TF isoform-pairs that show each type of binding modality (cooperativity, TF1 or TF2 antagonized, mutual antagonism, TF1 and/or TF2 independent binding, or no binding) across DNA-baits. Names in red indicate TFs for which alternative isoforms were studied...
Watanabe H, Sawada J-I, Yano K, Yamaguchi K, Goto M, Handa H (1993) cDNA Cloning of Transcription Factor E4TF1 Subunits with Ets and Notch Motifs. Mol. Cell. Biol. 13: 1385–1391 Suzuki F, Goto M, Sawa C, Ito S, Watanabe H, Sawada J-I, Handa H (1998) Functional interaction...
Tf1 insertion predominantly occurs closer to the 5′ end of genes, in regions known to have relatively open chromatin [78, 79]. These studies clearly argue for the relationships between open chromatin and preferential transposition sites. However, it should be noted that these TE insertions at ...
TF1 bacteriophage SPO1-encoded transcription factor 1bacteriophage SPO1-encoded transcription factor 1Prokaryotic genomes are compacted by association with small basic proteins, generating what has been termed bacterial chromatin. The ubiquitous DNA-binding protein HU serves this function. DNA-binding ...
Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter. We show here that NF-kappa B, an inducible B-cell-specific factor that binds the kappa immunoglobulin light chain gene enhancer, also binds the ...
Twenty-one of the novel ORFs show sequence similarities which suggest functions of their products, including a cyclin C, a MADS box transcription factor, mad2-like protein, telomere binding protein, topoisomerase II-associated protein, ATP-dependent DEAH box RNA helicase, G10 protein, ubiquitin-...
, 25.. Other members of the DNABII family include TF1 as well as the HU proteins from prokaryotes 20., 22., 23.. IHF participates in chromosome packaging, the regulation of at least 120 genes, the integration of the virus λ, the initiation of DNA replication, and the stabilizing of ...
Natural mitochondrial DNA (mtDNA) mutations enable the inference of clonal relationships among cells. mtDNA can be profiled along with measures of cell state, but has not yet been combined with the massively parallel approaches needed to tackle the compl