Chemical synthesis of DNA occurs in a 3′ to 5′ direction, which is the opposite ofDNA synthesisin the cell. Since chemicals cannot discern which group is the correct one for addition of the next nucleotide, thes
The major pathways of DNA double-strand break (DSB) repair are crucial for maintaining genomic stability. However, if deployed in an inappropriate cellular context, these same repair functions can mediate chromosome rearrangements that underlie various h
DNA synthesis in late mitosis promotes nuclear division Fig. 1: EdU nuclear incorporation occurs in G1 but not M-phase arrested cells. Nuclear EdU incorporation in G1 cells may reflect DNA synthesis in the nucleus and/or increased nuclear import of nucleotides. To test if EdU incorporation depe...
In what phase does DNA synthesis occur? In what part of the cell cycle does DNA replication occur? Is DNA replication and transcription the same? How does interphase prepare cells for mitosis? What process occurs after DNA replication?
Step-by-Step Solution:1. Understanding the Question: The question asks about the phase in which DNA synthesis occurs during the cell cycle.2. Identifying the Phases of Interphase: The ce
Mitosis: Mitosis is one type of cell division that occurs in eukaryotic organisms. This type of division specifically occurs in all body or somatic cells. The phases of mitosis include prophase, metaphase, anaphase, and telophase. Answer and Explanation:...
One of the more puzzling phenomena associated with postreplication repair is the observation that UV-irradiated mammalian cells recover the ability to synthesize DNA of the same size as that in unirradiated cells within a few hours after irradiation. This recovery occurs much sooner than one would...
The synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated (chromosome duplication). G2 Phase The cell prepares for division (mitosis). Gap before mitosis. Interphase Period between cell divisions where cell grows, develops, and functions. ...
Before a cell can reproduce, it must first replicate — or make a copy of — its DNA. Where DNA replication occurs depends upon whether the cell is a prokaryote or a eukaryote. DNA replication occurs in the cytoplasm of prokaryotes and in the nucleus of eukaryotes. Regardless of where DNA...
Replication protein A (RPA) binds to and protects ssDNA that occurs during DNA replication and upon DNA end resection in the context of homology-directed repair36,37. Congruously, its functions have been studied primarily in the S and G2 phase of the cell cycle. To assess heritable DNA ...