DNA is found in nearly all living cells. However, its exact location within a cell depends on whether that cell possesses a special membrane-bound organelle called a nucleus. Organisms composed of cells that contain nuclei are classified aseukaryotes, whereas organisms composed of cells that lack ...
2(a)), known as tetrads, hybridized through a Hoogsteen bonds. G-tetrads stack with cations to form a very stable G4 structure (Fig. 2(b)). G4s are able to form an intramolecular quartet within the same strand, or guanines on different DNA strands can assemble to form an ...
A metallo-DNA nanowire with uninterrupted one-dimensional silver array A metallo–DNA hybrid nanowire composed only of silver-mediated base pairs has been prepared and its crystal structure resolved by X-ray diffraction. The nanowire, which is 2 nm wide and whose length reaches the μm to mm ...
[2] Lindahl T. Instability and decay of the primary structure of DNA [J]. Nature. 1993; 362: 709-715. [3] Ganai R.A., Johansson E. DNA Replication—A Matter of Fidelity [J]. Mol. Cell. 2016;62:745–755. [4] Redon CE, Nakamura AJ,et al. Histone gammaH2AX and poly(ADP-rib...
DNA can perform its functions without falling apart because it is helical in shape and has a double-helix structure. The structure of DNA allows it to...Become a member and unlock all Study Answers Start today. Try it now Create an account As...
值得一提的是，Science China Life Science杂志Letter栏目发表中国科学院生物物理研究所许瑞明课题组题为“Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2”的文章，发布了人源的FACT复合物亚基SPT16, MCM2和组蛋白的复合体晶体结构。该结构表明，老核小体重新利用的单元应该是...
What is the role of phosphodiester bonds within the sugar-phosphate backbone of DNA? What is meant by the term “antiparallel?” Why is DNA with a high GC content more difficult to denature than that with a low GC content? In considering the structure of the DNA double helix, how would ...
The structure revealed that ISFba1 TnpB and reRNA form a complex with 1:1 stoichiometry (Fig. 5a–c). ISFba1 TnpB consists of an amino-terminal TAM-interacting domain (TID) and a non-target-strand recognition (REC1) domain, a target-strand recognition (REC2) domain, a reRNA-binding...
DNA synthesis is the biological process by which a deoxyribonucleic acid (DNA) molecule is created. In the cell, each of the two strands of the DNA molecule acts as a template for the synthesis of a complementary strand.Latest Research and Reviews Communication between DNA polymerases and Replica...
张勇研究组聚焦重复序列的突变机制、功能演化及转化研究,在重复基因与转座子两方面有较深的积累 (Cell 2024;Nature Ecology & Evolution 2022/2024; Nature Biotechnology 2023) 。为精准解析重复序列,研究组近年来致力于测序技术的开发;LILAP与已发表的二、三代高精度测序技术综述 (Genomics, Proteomics & Bioinformat...