2.6.A1Crick and Watson’s elucidation of the structure of DNA using model making. DNA分子有两条方向平行(antiparallel)的多核苷酸链组成,中间的碱基依靠氢键联系在一起,形成特殊的双螺旋结构。A与T以两个氢键结合(RNA中是A和U),G与C以三个氢键结合,这种结合方式叫碱基互补配对(co
2024年9月2日,南京大学陈加余课题组在Nature Chemistry杂志发表了题为“Chemoproteomic profiling unveils binding and functional diversity of endogenous proteins that interact with endogenous triplex DNA”的研究论文,首次系统性揭示了内...
Structural Biology Section, CRC Biomolecular Structure Unit, Institute of Cancer Research, London, UKHelge WeissigDepartment of Chemistry, Rutgers University, Piscataway, NJ, USAJohn Wiley & Sons, Inc.Neidle,S., Schneider,B. and Berman,H.M. (2003) Fundamentals of DNA and RNA structure. In: ...
RNA容易突变的特性反而给了病毒更多的变异机会,以此筛选出更适合的变种来侵染更多细胞。参考资料:[1] 为什么 DNA 能形成双螺旋结构(并成为主要的遗传物质)而 RNA 不能?[2] Rana, T. Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol8, 23–36 (...
the structure of DNA and RNA文献资料.pdf,42636_06_p1-33 12/12/02 7:03 AM Page 1 C H A P T E R 6 The Structures of DNA and RNA he discovery that DNA is the prime genetic molecule, carrying all O U T L I N E the hereditary information within chromosomes, i
Portugal, Franklin H. A century of DNA : a history of the discovery of the structure and function of the genetic substance. Jack S. Cohen. Cambridge, Mass.: MIT Press. ISBN 978-0-262-16067-4. OCLC 2964854. 声明:以上文字和图片只作科学...
There are three major differences in the structure of RNA and DNA. First, RNA only exists as a single-strand while DNA can be double-stranded or...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough...
A protein structural domain that binds DNA and RNA, and that is found most commonly in transcription factors. It consists of a helix–turn–helix structure of 60 amino acids. GAR domain A Gly- and Arg-rich motif that adopts a repeated β-turn structure. It is found most commonly in prote...
Despite wide interest in nucleic acid triple helices, there has beenno stereochemically satisfactory structure of an RNA triple helixin atomic detail. An RNA triplex structure has previously been proposed based on fiber diffraction and molecular modeling [S. Arnott and P. J. Bond (1973) Nature ...
RNAstructure through post-transcriptional modifications. The differentpropensities to form Hoogsteen base pairs in B-DNA and A-RNA may help cellsmeet the opposing requirements of maintaining genome stability, on the onehand,...