Allemand JF, Bensimon D, Lavery R, Croquette V. Stretched and overwound DNA forms a Pauling-like structure with exposed bases. Proc Natl Acad Sci U S A. 1998 Nov 24; 95 (24): 14152–7. Y Mitsui, R Langridge, B E Shortle, C R ...
structure resembling a ladder twisted into a spiral, called adouble helix.Each rung is made up of two chemical bases, callednucleotides,that are joined together by hydrogen bonds. There are four kinds of nucleotides in a DNA molecule: cytosine, guanine, adenine, and thymine—C, G, A, and ...
Now let’s talk about the structure of DNA. 现在让我们来谈谈DNA的结构。 Think of DNA’s structure as a ladder whose rungs are made up of different bases and sides as sugar –phosphate. 把DNA的结构想象成一个梯子,阶梯是由不同的碱基组成的,两边是糖-磷酸。 Each composition of this nitrogeno...
DNA damages give rise to mutations and epimutations that, by a process of natural selection, can cause progression to cancer. First, we describe the distinguishing characteristics of DNA damage, mutation and epimutation. DNA damage is a change in the basic structure of DNA that is not itself ...
The bases on each strand are joined to the bases on the other strand with hydrogen bonds, but different bases have different chemical structures. Cytosine and thymine (and uracil in RNA) are pyrimidines, containing one ring. Adenine and guanine are purines, containing two rings. The pyrimidine...
There are two major classes of chemical probes of DNA structure: those that demonstrate no inherent base preference but are sensitive to DNA geometry, such as groove widths and chirality, and those that are base-specific, detecting bases in distorted regions of the helix. The former bind to DN...
coli hemolysin E (Hlye, ClyA, SheA): X-ray crystal structure of the toxin and observation of membrane pores by electron microscopy. Cell 100, 265–276 (2000). CAS PubMed Google Scholar Huang, G. et al. Electro-osmotic vortices promote the capture of folded proteins by PlyAB nanopores....
Instability and decay of the primary structure of DNA. Nature, 362, 709-715. Liu S, Kruse S, Scherler D, Ree RH, Zimmermann HH, Stoof-Leichsenring KR, Epp LS, Mischke S, Herzschuh U (2021a). Sedimentary ancient DNA reveals a threat of warming-induced alpine habitat loss to Tibetan...
et al. WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nature Struct. Mol. Biol. 13, 414–422 (2006). Article CAS Google Scholar Swanson, C., Saintigny, Y., Emond, M. J. & Monnat, R. J. Jr. The Werner syndrome protein has separable...
Structure, Synthesis, and Application of Nanoparticles Engineered Nanoparticles Book2016,Engineered Nanoparticles Ashok K.SinghPhD Explore book 5.2.5Unique Applications of DNA Dendrimers Unique applications ofDNAdendrimersinclude the following: DNA as a template for self-assembly: DNA scaffolds are likely to...