The first DNA sequence databaseJeffrey M. Perkel
Strelets and Lim [13] were interested in producing a compressed database that could be used interactively in much the same way as the original database. This was facilitated in part by the fact that their approach never requires recursive decoding of sequences – each sequence is encoded in t...
Once a gene has been provisionally identified, the database is searched for homologies—similar sequences in other organisms. When a homology is found, it often hints at the function of the gene. Even the nematode Caenorhabditis elegans and the fruit fly Drosophila contain genes that exist in ...
The Reference Sequence (RefSeq) collection provides a comprehensive, integrated, non-redundant, well-annotated set of sequences, including genomic DNA, transcripts, and proteins. RefSeq sequences form a foundation for medical, functional, and diversity studies. They provide a stable reference for genom...
近日,军事医学研究院伯晓晨和郑晓飞团队在Briefings in Bioinformatics杂志上发表方法学综述:Computational methods for the prediction of chromatin interaction and organization using sequence and epigenomic profiles,分类总结了基于DNA序列和基因组表观修饰信息预测染色质相互作用和高级结构的48种计算方法,评估了不同方法的...
目前最常用来做指纹图谱和纯度鉴定的方法是SSR( Simple Sequence Repeats,简单序列重复)和 SNP( Single Nucleotide Polymorphism, 单核苷酸多态性)标记。 SSR标记 SSR 标记的特点是等位变异类型丰富,用较少的核心标记就能区分各个品种。对 SSR 标记的检...
The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the autosomal origin of the
Repbase Update, a database of repetitive elements in eukaryotic genomes Repbase Update (RU) is a database of representative repeat sequences in eukaryotic genomes. Since its first development as a database of human repetitive sequences in 1992, RU has been serving as a well-curate... ...
Sequencher has the tools you need to get results. Sequencher has integrated the comprehensive Cufflinks suite for in-depth transcript analysis and differential gene expression of your RNA-Seq data. Sequencher can easily generate unique visualizations of your RNA-Seq data with custom plots and charts ...
4d). In addition, domains shifting to earlier RT were enriched for MERVL sequences, in particular the MERVL promoter (LTR, MT2_Mm) and internal sequences (MERVL), but not for other endogenous retroviruses, LINE-1 or SINE-B2 elements (Fig. 4e). This shift to earlier RT matches a ...