DNA replication What is the name of the process of making a copy of the DNA? mutation an error occurs in making a copy, we say that the DNA contains a ___. helicase What is the name of the enzyme that unwinds DNA? Polymerase What is the name of the enzyme that copies the DNA/ma...
In the absence of Mus81 endonuclease activity, DNA synthesis is slowed and replication initiation events are more frequent. In addition, Mus81-deficient cells fail to recover from exposure to low doses of replication inhibitors and cell viability is dependent on the XPF endonuclease. Despite an ...
Mammalian chromosome replication starts from distinct sites; however, the principles governing initiation site selection are unclear because proteins essential for DNA replication do not exhibit sequence-specific DNA binding. Here we identify a replicati