Considering DNA replication along the 5'-->3' template strand, what event takes place first? 连锁遗传定律,:就是原来为同一亲本所具有的两个性状,在F2中常常有连系在一起遗传的倾向,这种现象称为连锁遗传。 基因,gene,基因是具有遗传效应的DNA片断 基因组,Genome:___中的全套___为一个基因组,或是单倍...
The initiation of cellular DNA replication takes place at a single site (e.g., oriC of E. coli) or multiple specific sites (in higher eukaryotes) of DNA called origins of replication (ori). The temporal site of dsDNA where the replication occurs is called a “replication fork.”...
annealing can be determined by adjusting temperature and ionic strength. DuringDNA replicationin the cell the two strands of DNA are separated so that each may serve as atemplatefor replication of a new opposite strand, complementary to the original. Replication of DNA in nature takes place by ...
DNAReplication,Recombination,andRepairGuo-MinLi(李国民),Ph.D.ProfessorJamesGardnerEndowedChairinCancerResearchUniversityofKentuckyCollegeofMedicin..
The initial unwinding of origin DNA during replication initiation must take place after assembly of the MCM double hexamer, but this process is poorly understood at a molecular level11. Our structure of the yeast MCM double hexamer bound to duplex DNA can be compared to the structure of the ye...
Replication stress (RS) is a major source of genomic instability and is intrinsic to cancer cells. RS is also the consequence of chemotherapeutic drugs for treating cancer. However, adaptation to RS is also a mechanism of resistance to chemotherapy. BRCA
Extracellular vesicle (EV) secretion is a highly conserved evolutionary trait in all organisms in the three domains of life. The packaging and release of EVs appears to be a bulk-flow process which takes place mainly under extreme conditions. EVs partici
DNA double-strand breaks (DSBs) can be caused by environmental agents such as radiation and drugs1,2,3and endogenous metabolism such as transcription and replication stress4,5. For example, normal metabolism has been estimated to cause ~1–50 DSBs per human cell per day6,7. Consequently, fas...
p pBackground/p pChloroplasts are the green plastids where photosynthesis takes place. The biogenesis of chloroplasts requires the coordinate expression of... X Zhou,Z Fei,TW Thannhauser,... - 《Bmc Plant Biology》 被引量: 29发表: 2011年 Chloroplast DNA replication is regulated by the redox...
One of these mechanisms, transposable or mobile elements, are segments of DNA encoding genes that assist in DNA excision, replication and integration of the elements into new regions of the genome. Until recently transposable elements (TEs) have been considered parasitic or selfish DNAs that contrib...