DNA origami structures with larger sizes and more complex conformations are desired to accomplish sophisticated tasks. Extending the length of the scaffold is a direct way to build larger DNA origami objects16,17,18. Alexandria and colleagues produced an ultralong 51-knt ssDNA scaffold using a λ/...
DNA origami structures with larger sizes and more complex conformations are desired to accomplish sophisticated tasks. Extending the length of the scaffold is a direct way to build larger DNA origami objects16,17,18. Alexandria and colleagues produced an ultralong 51-knt ssDNA scaffold using a λ/...
Fabricating nanoelectronic circuits of the future just got a lot more interesting, thanks toDNAorigami. The quest for ever-smaller electronic components led an international group of researchers to explore using molecular building blocks to create them. DNA is able to self-assemble into...
Illustration shows the basic process used to design DNA origami nanostructures. First, a wireframe of the intended target design is made. The software then translates this into a plan for the routing of DNA scaffold and staple strands, which assemble to form the desired shape. Credit: Biodesign...
For the nanofilm structure, we synthesized various unique 3-dimensional anti cancer drug incorporated DNA origami structures (hairpin, Y and X shaped) and assembled with peptide via layer-by-layer (LbL) deposition method. The key to the successful application of these nanofilms requires a novel ...
nanopores by fitting them with cover plates made of DNA. These nanoscale cover plates, with central apertures tailored to various "gatekeeper" functions, are formed by so-called DNA origami – the art of programming strands of DNA to fold into custom-designed structures with specified chemical ...
The illustration represents the folding of the tall-rectangle DNA origami as it slides down a conceptualized folding funnel.Dr. Isaac GállegoSchool of Chemistry and BiochemistryProf. Martha A. GroverSchool of Chemistry and BiochemistryProf. Nicholas V. Hud...
SPECTRA exemplifies the integration of advanced DNA origami with plasmonic nanotechnology, providing a highly specific and sensitive tool for the early detection of metastatic cancer cells. The scalability and reproducibility of the DNA origami technique further enhances SPECTRA’s clinical use, marking a...
ATTACHMENT OF METAL NPs TO 3D DNA ORIGAMI ASSEMBLIES Nanostructures created using the DNA origami technique are not limited to 2D sheets. Various fine 3D structures have also been produced. Zhao et al.42 recently constructed an interesting 3D DNA origami-AuNP composite (Figure 6a). A DNA ...
Fig. 1: Design of an aptamer-functionalized DNA origami nanoarray for anticoagulation in hemodialysis. aSchematic illustration of the construction of the aptamer-loaded nanoarray by DNA origami, and the specific binding and inhibition of thrombin. Single-stranded M13mp18 DNA (M13) is folded by annea...