the assembly of complex arrays. An efficient solid-state synthesis for producing surface-grafted, robust nanotubes has now been devised. Rungs are incorporated in a stepwise manner so that each one is addressable. Using fluorescent tags, the nanotube growth was visualized at the single-molecule ...
GMT makes it difficult to predict the specificity of a probe without testing it, highlighting the need for a tool to rapidly screen assay probes. By pairing single-molecule nanopore measurements with DNA nanotechnology, we have created a system that can uniquely and accurately assess the specific ...
Each unit of a phosphate, a sugar molecule, and base called a nucleotide is about 0.34 nm long. The specific binding through hydrogen bonds between adenine (A) and thymine (T), and cytosine (C) and guanine (G) can result in the joining of two complementary single-stranded (ss) DNA to...
The canonical conformation of the DNA molecule is a double helix which under physiological conditions forms a stable structure known as B DNA. However, certain environments and sequence motifs favor other DNA conformations, known as non-canonical secondary structures. Moreover, many of the structures ...
Increasing the temperature of a solution containing DNA causes DNA strands to separate. The temperature at which half of the double stranded DNA molecules are converted to single stranded DNA is defined as the melting temperature of the DNA molecule (Tm). The Tm depends on the length and the ...
Which scientists are given most of the credit for describing the molecular structure of DNA? DNA Structure Watson and Crickproposed thatDNAis made up of two strands that are twisted around each other to form a right-handed helix. The two DNA strands areantiparallel, such that the 3ʹ end ...
DNA molecule is wrapped around specific proteins called histones. Histones are positively charged proteins. Eight such histone proteins form a unit...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tou...
Physical activity is well known for its multiple health benefits and although the knowledge of the underlying molecular mechanisms is increasing, our understanding of the role of epigenetics in long-term training adaptation remains incomplete. In this in
The commercialization of DNA tagging is a growing trend that demonstrates the increasing practicality of this novel approach. This interdisciplinary technology is based on the distinctive characteristics of DNA as a molecule that can remain stable in varying environmental conditions and store data following...
Using a small molecule that non-covalently crosslinks thymine residues, we show that this dynamic morphology can be “frozen” into stable fibers that retain low dispersity. This work defines a new class of sequence-defined DNA oligomers called ‘curlamers’, whose folding behavior is precisely ...