英文检索词为“DNA hydrogel,drug delivery,bone defect,osteogenic differentiation,osteogenic factor”,中文检索词包括“DNA水凝胶、药物输送、基因治疗、应用、细胞培养、骨缺损、成骨分化、成骨因子”,检索时间为2021年1月至4月,主要检索...
英文检索词为“DNA hydrogel,drug delivery,bone defect,osteogenic differentiation,osteogenic factor”,中文检索词包括“DNA水凝胶、药物输送、基因治疗、应用、细胞培养、骨缺损、成骨分化、成骨因子”,检索时间为2021年1月至4月,主要检索DNA水凝胶的类型,及其在药物输送以及骨组织工程...
Finally, DNA hydrogel-based delivery platforms for different types of drugs are detailed. With the emergence of gene therapy, this review also gives future prospects for combining DNA hydrogels with the gene editing toolbox.doi:10.1016/j.addr.2020.07.018Fangli Mo...
在随后的几年,围绕这两项技术涌现出许多细分和延伸的研究,生物可降解聚合物(biodegradable polymers)、聚合物药物递送系统(polymeric drug delivery systems)研究数量迅速增加并得到持续关注,从市场信息来看,这些突破在后续先后被应用到产业领域中;2020年至今,3D打印(3d printing)、exosomes、机器学习(machine learning...
Another strategy is to use the enzymatic action of the DNA hydrogel to disintegrate the hydrogel structure, resulting in a slow release of the encapsulated drug. Zhang et al. [95] used an enzyme-responsive DNA hydrogel (DSH) as a metformin (MET) delivery vehicle for the treatment of ...
其中,以nanoparticles、chitosan、controlled release、curcumin、hydrogel为聚类簇的研究热点,整体发文趋势呈上升状态,发文数量在2023年达到峰值。 近三年各国研究产出排名 在该研究方向中,Top10国家合计贡献了研究总数的43.77%。其中,中国产出最高,共16685篇文献,占比15.93%;美国次之。总产出7673篇,占比7.32%。印度位居...
In summary, CDs mediated DNA hydrogel was used as drug delivery vehicle for sustained release of drug. The amine functionalized surface of CDs was conjugated to C-rich ssDNA and processed for network formation through the formation of DNA i-motif structure. The intense fluorescence of the CDs wa...
5c, d). These findings suggest that DNA hydrogel constructs are ideal vectors for the delivery of DNA-damaging agents such as Dox in cancer cells. Testing of QDHs in xenograft model We sought to test whether ZnS-QDH could be used as drug carriers in an animal model. The toxicity in mice...
其中,以nanoparticles、chitosan、controlled release、curcumin、hydrogel为聚类簇的研究热点,整体发文趋势呈上升状态,发文数量在2023年达到峰值。 近三年各国研究产出排名 在该研究方向中,Top10国家合计贡献了研究总数的43.77%。其中,中国产出最高,共16685篇文献,占比15.93%;美国次之。总产出7673篇,占比7.32%。印度位居...
Then, new concepts, properties, and applications are highlighted such as DNA鈥恇ased biosensor devices, drug delivery platforms, and cell scaffolds. With the 2018 Nobel Prize in Physiology or Medicine being awarded to cancer immunotherapy underscoring the importance of this therapy, DNA hydrogel ...