整个循环下来，DNA分子运动了12bp。因为每个DNA螺旋包含10.5 bp，所以DNA被转位的同时，FtsK也要相对于...
因为一个DNA转录位点可以抽象为空间中的一个粒子，粒子随机运动和转录体接触，导致活跃转录，这其实就是...
2023年1月5日,来自美国斯坦福大学医学院的Tobias Meyer团队在Molecular Cell杂志在线发表了题为CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis的文章,揭示了细胞如何在S早期确保DNA只复制一次。研究人员发现S...
When viruses infect a cell, they inject their DNA. 当病毒感染一个细胞,它们会插入自身的DNA。 And in a bacterium, the CRISPR system allows that DNA to be plucked out of the virus, 在一个细菌中,CRISPR系统可以把病毒的DNA拔掉, and inserted in little bits into the chromosome -- the DNA of...
在沃森领悟到碱基配对的同时,克里克还从富兰克林MRC报告 (图9) 中发现了一个只有他能领会的要点: A型DNA纤维由于接近晶体,富兰克林运用帕特森函数(cylindrical Patterson function)的计算发现,其晶胞(unit cell) 属于面心单斜类型 (face-centered monoclinic)。由于DNA分子中存在大量的不对称碳原子,描述这类单斜晶胞对称...
A CELL HAVING A CERTAIN FUNCTION IN A PROCESS,CONTAINING RECOMBINANT DNA ENCODING AT LEAST ONE ENZYME,RECOMBINANT DNA,ENZYME FOR WHICH THE RECOMBINANT DNA ENCODES AND USES THEREOF 来自 掌桥科研 喜欢 0 阅读量: 6 申请(专利)号: ZA19910004714 申请日期: 1991-06-19 公开/公告号: ZA914714B ...
Characterization of deoxyribonucleic acid synthesis and the transition from maternal to embryonic control in the 4-cell porcine embryo. These studies were conducted to identify the point during the 4-cell stage at which the porcine embryo begins to control development. Reproductive tracts o... Schoenb...
继2023年以共同通讯作者身份与李莉等合作在Cell上发表新一代谱系追踪小鼠DARLIN后,时隔一年,2025年1月16日,西湖大学的王寿文团队与李莉研究员再次合作,在Nature Methods上发表了文章High-resolution, noninvasive single-cell lineage tracing in mice and humans based on DNA methylation epimutations,开发谱系追踪新的...
in normal and diseased cells, and it can potentially function as a biomarker. Although these findings challenge the view that methylation is generally instructive for gene silencing, several open questions remain, including how methylation is targeted and recognized and in what context it affects ...
2020年3月12日,付向东实验室在Cell上发表文章Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation,首次报道了SR蛋白特异性剪接激酶SRPK1在小鼠受精卵早期发育过程中具有重要功能:即母源SRPK1激酶负责催化进入卵细胞的精子DNA快速起始解压缩,协助启...