AptamerProtein activity regulationSystematic evolution of ligands by exponential enrichment(SELEX)Membrane receptorThrombinProteins play a central role in all domains of life,and precise regulation of their activity is essential for understanding the related biological processes and therapeutic functions.Nucleic...
Challenges to Design and Develop of DNA Aptamers for Protein Targets. I. Optimization of Asymmetric PCR for Generation of a Single Stranded DNA Library.AptamerAsymmetric PCRRandom poolSELEXSingle stranded DNAAptamers, or single stranded oligonucleotides, are produced by systematic evolution of ligands by...
A Logical Molecular Circuit for Programmable and Autonomous Regulation of Protein Activity Using DNA Aptamer-Protein Interactions. J. Am. Chem. Soc. 2012; 134 :20797–20804.Han D., Zhu Z., Wu C, et al. (2012). A logical molecular circuit for programmable and autonomous regulation of ...
Cells (AptaPIC) is an integrated set of methods that allows for: (i) the development of an aptamer pool for a single protein target in the context of a crude cell lysate, and (ii) the subsequent use of the developedaptamer pool inaffinity purificationof the target protein ...
名称编号规格价格手册 C反应蛋白DNA型适配子C-Reactive Protein(CRP)DNA Aptamer (Kd=3.51 nM)21-108810ug询价 英文名称:C-Reactive Protein(CRP)DNA Aptamer (Kd=3.51 nM) 运输:常温 保存:常温 有效期:1年 货期:4周 其他: 产品介绍: Order Online在线订购...
2024年5月,张宏博教授在《Nature Communications》杂志【IF16.6,Q1】发表题名为“Development of Aptamer-DNAzyme based metal-nucleic acid frameworks for gastric cancer therapy.”——开发基于适体-DNAzyme的金属核酸框架用于胃癌治疗...
英文名称:Retinol-Binding Protein-4(RBP4)DNA Aptamer (Kd=201 nM) 运输:常温 保存:常温 有效期:1年 货期:4周 其他: 产品介绍: Order Online在线订购 订货信息 产品名称* 申请类型* 套数* 推荐人 真实姓名* 邮寄地址* 所属单位 电子邮箱* 联系电话* ...
如有任何版权问题,请随时与我们联系! Brennan J D, Bialy R M, Ali M M, et al. Protein‐Mediated Suppression of Rolling Circle Amplification for Biosensing with an Aptamer‐containing DNA Primer[J]. Chemistry-A European ...
Modulation of Aptamer-Ligand-Binding by Complementary Oligonucleotides: A G-Quadruplex Anti-Ochratoxin A Aptamer Case Study. PMID: 35563267 Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition. PMID: 33182593 Epigenomic Features and Potential Functions of K(+) and Na(+) Favorable...
In particular, aptamer microarrays have excellent prospects to assist drug design and development. High-throughput screening of appropriate libraries of compounds against validated targets is one of the major activities in drug discovery [35]. High-throughput screening arrays typically require protein-...