The complementarity of the two strands in the DNA double helix provides a mechanism for the storage and processing of genetic information. Now, an alternative ‘strand commutation’ mechanism of data processing with DNA/RNA has been revealed based on the reversible low-affinity interactions of essent...
For PCR-amplified libraries and RNA-Seq libraries, unique molecular identifiers (UMI) may be included to enable tracking of every library fragment and monitoring of deviations during library amplification [11]. Figure 13. Multiplex s...
The noncoding RNA LINP1 acts as a scaffold that links Ku and DNA-PKcs and enables efficient DNA double-strand-break repair through nonhomologous end joining (NHEJ), thereby enhancing the resistance of triple-negative breast cancer cells to radiation and
Structure and spatio temporal expression of the full length DNA complementary to RNA coding for α2 type I collagen of zebrafish 来自 Semantic Scholar 喜欢 0 阅读量: 72 作者:GM Dubois,Z Haftek,C Crozet,R Garrone,DL Guellec 摘要: Twenty distinct genetic types of collagen have been identified...
摘要 转染体外转录的RNA编码肿瘤相关抗原的树突状细胞(DC)的过继转移最近已进入临床试验，作为一种有前途...
RNAs, like that of an RNA virus. Similar to its effect on virus entry, this activity of SERINC5 is counteracted by HIV and SIV Nef. Overall, these observations indicate that the roles of SERINC5 in host defense extend beyond viruses and that it can also protect from multiple DNA ...
8. Site & SequenceThis map view displays the DNA sequence with restriction sites above, and translations below. Feature annotations are displayed between the translations and the 52、DNA sequence. 9. WorksheetDisplays the DNA sequence as a linear graph with restriction sites above, and feature ...
DNASTAR software is trusted by tens of thousands of researchers around the world because of its well-deserved reputation for accuracy, versatility, and ease of use. Our cutting-edge applications expertly handle dozens of popular bioinformatics workflows, including molecular cloning and primer design; ...
and annotate genes Predict coding regions and splice sites Locate repeats, patterns, or areas matching known sequence data Simulate agarose gel electrophoresis * MapDraw Locate restriction sites Create six types of linear and circular maps View all six reading frames with sites and features * ...
Long noncoding RNAs (lncRNAs) are known to regulate DNA damage response (DDR) and genome stability in proliferative cells. However, it remains unknown whether lncRNAs are involved in these vital biological processes in post-mitotic neurons. Here, we report and characterize a lncRNA, termed Brain...