烷基腺嘌呤DNA糖基化酶AAG(3-methyladenine DNA glycosylase)可以识别包括3-甲基腺嘌呤(3-methyladenine,3-MA),7-甲基鸟嘌呤(7-methylguanine,m7G),氧化腺嘌呤1,N6-乙醇腺嘌呤(1,N6-ethenoadenine, εA)和脱氨腺嘌呤次黄嘌呤(Hypoxanthine)在内的碱基损伤。在人类中,AAG的表达改变与微卫星不稳定性、自发移码突变...
烷基腺嘌呤DNA糖基化酶AAG (3-methyladenine DNA glycosylase)可以识别包括3-甲基腺嘌呤(3-methyladenine,3-MA),7-甲基鸟嘌呤(7-methylguanine,m7G),氧化腺嘌呤1,N6-乙醇腺嘌呤(1,N6-ethenoadenine, εA)和脱氨腺嘌呤次黄嘌呤(Hypoxanthine)在内的碱基损伤。在人类中,AAG的表达改变与微卫星不稳定性、自发移码突...
烷基腺嘌呤DNA糖基化酶AAG (3-methyladenine DNA glycosylase)可以识别包括3-甲基腺嘌呤(3-methyladenine,3-MA),7-甲基鸟嘌呤(7-methylguanine,m7G),氧化腺嘌呤1,N6-乙醇腺嘌呤(1,N6-ethenoadenine, εA)和脱氨腺嘌呤次黄嘌呤(Hypoxanthine)在内的碱基损伤。在人类中,AAG的表达改变与微卫星不稳定性、自发移码突...
烷基腺嘌呤DNA糖基化酶AAG (3-methyladenine DNA glycosylase)可以识别包括3-甲基腺嘌呤(3-methyladenine,3-MA),7-甲基鸟嘌呤(7-methylguanine,m7G),氧化腺嘌呤1,N6-乙醇腺嘌呤(1,N6-ethenoadenine, εA)和脱氨腺嘌呤次黄嘌呤(Hypoxanthine)在内的碱基损伤。在人类中,AAG的表达改变与微卫星不稳定性、自...
烷基腺嘌呤DNA糖基化酶AAG(3-methyladenine DNA glycosylase)可以识别包括3-甲基腺嘌呤(3-methyladenine,3-MA),7-甲基鸟嘌呤(7-methylguanine,m7G),氧化腺嘌呤1,N6-乙醇腺嘌呤(1,N6-ethenoadenine, εA)和脱氨腺嘌呤次黄嘌呤(Hypoxanthine)在内的碱基损伤。在人类中,AAG的表达改变与微卫星不稳定性、自发移码突变...
ZielenkiewiczInstitute of Biochemistry and BiophysicsBiochemical and biophysical research communicationsD. Plochocka, A. Kierzek, T. Obtulowicz, B. Tudek, P. Zielenkiewicz, 3-Methyladenine-DNA glycosylase I from Escherichia coli-computer modeling and supporting experimental evidence, Biochem. Biophys. ...
别名MPG; N-methylpurine-DNA glycosylase isoform a; DNA 3 methyladenine glycosylase; 3 alkyladenine DNA glycosylase; AAG; ADPG; Alkyladenine DNA glycosylase; anpg ; APNG; MDG; N methylpurine DNA glycosirase; CRA36.1; MDG; Mid1; PIG11; PIG16; 3MG_HUMAN. ...
has produced structures representing three discrete reaction steps. The NMR structure of 3-methyladenineglycosylaseI revealed its place among the structural families of DNA glycosylases and the X-ray structure of SMUG1 likewise confirmed that this protein is a member of theuracil DNA glycosylasesuperfam...
别名MPG; N-methylpurine-DNA glycosylase isoform a; DNA 3 methyladenine glycosylase; 3 alkyladenine DNA glycosylase; AAG; ADPG; Alkyladenine DNA glycosylase; anpg ; APNG; MDG; N methylpurine DNA glycosirase; CRA36.1; MDG; Mid1; PIG11; PIG16; 3MG_HUMAN. ...
Abstract The activities and the expression of 3-methyladenine glycosylase (3-meAde gly) and O6-alkylguanine-DNA-alkyltransferase (O6 ATase) were investigated in ten human cancer cell lines. Both 3-meAde gly and O6 ATase activities were variable among different cell lines. mRNA levels of the ...