The reaction solution was poured into ice-water (300 g), and the product was extracted with isopropyl ether (500 ml)..; The isopropyl ether layer was washed with 10percent aqueous phosphoric acid solution and aqueous sodium chloride solution, successively, and dried (over MgSO4), and the sol...
To study the reaction between a β-diketone and dimethyl sulphoxide (DMSO)/acetic anhydride to synthesize a novel chemical entity. o-Hydroxyacetophenone was esterified with p-chlorobenzoic acid using POCl3. The obtained ester was subjected to a B.V. rearrangement in a solution of KOH in pyridine...
chloride, then charged with a solution of N,N-diisopropylethylamine (36 mL, 200 mmol) in 5 mL of methylene chloride and the reaction solution is warmed to −45°C over a period of 30 min. N,N-Diisopropylethylamine is added over 5 min, then the reaction flask is removed from the C...
DMS formation can be easily prevented by oxidizing the DMSO in the effluent to DMSO2. DMSO2is inert to biological action. A 1% aqueous solution of DMSO treated with 10% excess sodium hypochlorite, for example, oxidizes completely within 2 hours at 25°C....
1. Used as a reaction medium for aromatic hydrocarbon extraction, resins and dyes, as well as a solvent for acrylic fiber polymerization and spinning.2. It can be used as an organic solvent, reaction medium, and intermediate in organic synthesis....
With a 12-residue peptide, CY-12( lo), disulfide formation was observed to be completed in about 1 h when the volume ratios of DMSO were between IO and 30%. The rates increased as the concentration of DMSO increased. At 40-50% DMSO, the reaction was completed within 0.5 h. On the ...
3.ReactionwithMetals17 4.ReactionwithStrongBases-DimsylIon17 5.ReactionwithAcidHalides18 6.ReactionwithAcidAnhydrides18 7.HalogenationofDMSO19 8.ReactionwithPhenolsandAniline19 9.AlcoholOxidationwithDMSO20 a)AceticAnhydride21 b)TrifluoroaceticAnhydride21 c)Dicyclohexylcarbodiimide21 d)PhosphorusPentoxide22 e)...
Overall, the outlined process involving DMSO and acetic acid as co﹕olvent has a computed energy demand on a par with state﹐f‐the art amine‐based processes. However, the insufficient chemical stability of DMSO poses major limitations on processes based on this solvent....
Overall, the outlined process involving DMSO and acetic acid as co‐solvent has a computed energy demand on a par with state‐of‐the art amine‐based processes. However, the insufficient chemical stability of DMSO poses major limitations on processes based on this solvent....
Overall, the outlined process involving DMSO and acetic acid as co-solvent has a computed energy demand on a par with state-of-the art amine-based processes. However, the insufficient chemical stability of DMSO poses major limitations on processes based on this solvent....