West University, Potchefstroom, South Africa 4 Hatter Institute for Cardiovascular Research in Africa & IIDMM, Cape Heart Centre, University of Cape Town.R... R Dolman,E Wentzel-Viljoen,J Jerling,... 被引量: 0发表: 2013年 加载更多研究点推荐 Molecular Medicine ...
Department of Hematology, Oncology & Cardiovascular medicine, Kyushu University Hospital, Fukuoka, JapanRyunosuke MachidaClinical Research Support Office, National Cancer Center Hospital, Tokyo, JapanRyo SadachiClinical Research Support Office, National Cancer Center Hospital, Tokyo, JapanAkihiro Hirakawa...
12月11日,默沙东对外宣布,欧洲药品管理局(EMA)人用药品委员会(CHMP)对有关Keytruda(pembrolizumab,帕博利珠单抗)的新适应症采信了积极意见,建议批准Keytruda作为微卫星高度不稳定型(MSI-H)或错配修复缺陷型(dMMR)结直肠癌成年患者的单药一线治疗方案。 该建议是基于关键的III期临床KEYNOTE-177(NCT02563002)试验结果...
We discuss the potential use of our model for identifying FH patients in a cardiovascular clinical setting, and highlight the importance of choosing the control population of patients accordingly. The goal of our efforts is to identify FH patients for the purpose of alerting physicians and ...
Responses ranged from 10% to 50% tumour regression in the remaining 7 patients. After a median follow-up of 9.8 months, 1 patient with pT3, pN1 disease and no evidence of pathological response had disease recurrence and another had died as a result of a disease-unrelated cardiovascular ...
Mlh1-knock-out-driven mismatch-repair-deficient (dMMR) tumors can be targeted immunologically. By applying therapeutic tumor vaccination, tumor growth is d