Diffuse Midline Glioma (DMG), H3K27M altered, confers a dismal survival of 9-15 months and has a non-inflammatory tumor immune microenvironment (TIME). Radiation therapy (RT) is the mainstay treatment for DMG and has been shown in other cancers to recruit an immune component. However, the...
Formerly of HENRY COW, THE ART BEARS, NEWS FOR BABEL & RECOMMENDED RECORDS (ReR) has been creating an ongoing series of podcasts called the Probes series. I am often fascinated at listening to each of these as Mr. Cutler does an incredible job of showing a deep history of Creative Music ...
has long been a favorite of mine,having played with Altered States & Ground Zero, as well as working with a diverse array of international musicians: Shelley Hirsch, Tatsuya Yoshida, Mani
Globally decreased histone 3, lysine 27 tri-methylation (H3K27me3) is a hallmark of H3K27-altered diffuse midline gliomas (DMGs) and group-A posterior fossa ependymomas (PFAs). H3K27-altered DMGs are largely characterized by lysine-to-methionine mutations in histone 3 at position 27 (H3K...
Consistent with this pattern, we identified high ACVR1—a gene frequently altered in H3.1-mutant DMGs—expression to be associated with: (a) worse survival in PFAs, and (b) upregulation of path- ways that were also enriched in ACVR1-mutated gliomas. We additionally characterized common and ...
Every Tuesday night here at DMG, we have some Free Live Creative Music and something magical happens. Our sonic environment is altered by each set, from two to five, and I am reminded of the provocative and healing qualities of live music. Sometimes I am not feeling so great or I am ti...
As far as I can tell, Mr. Poss plays all of the instruments on this solo disc. While Mr. Poss’ earlier discs were experimental with altered guitars, this one actually has that chugging, slow burning Band of Susans-like sound. Layers of interconnected guitars all buzzing together wi...
“interne Gezeiten†both clarinetists play their lines around one another, bending certain notes to keep things off balance tonally. There are some strange sounds going here, which are hard to identify, similar to gamelan gongs which are somehow detuned or altered. ...
an annual journey that’s I’ve been doing every year since 1987, except for the two years when the fest moved from October to May and the year after the pandemic when only Canadians could attend. I attended 18 sets of music over four days and I feel altered by the expe...
altered, such that the essential voice of the living sound sources remain identifiable. The development of this framework is a direction that Prime's music has been moving towards for some years now, and this box set collects various recordings made between 1990 and 2019 that fall into the ...