DM-β-CDEnantiomeric separations of several b-amino alcohol drugs, i.e., phe- nylephrine, epinephrine, norepinephrine, synephrine, and chlorpre- naline were performed by capillary electrophoresis using DM-b-CD as a chiral selector. Five test solutes were baseline resolved...
Dm-beta-cdZone electrophoresisCyclodextrinResolutionChromatographyEnantiomeric separations of several beta-amino alcohol drugs, i.e., phenylephrine, epinephrine, norepinephrine, synephrine, and chlorprenaline were performed by capillary electrophoresis using DM-beta-CD as a chiral selector. Five test solutes...
The solubility diagram of simvastatin with each beta CD derivative could be classified as AL-type, indicating soluble complex formation of 1: 1 stoichiometry. Among the above beta CD derivatives DM beta CD was found to be the ideal complexing agent for improving drug solubility. The simvastatin ...