Notch is a pleiotropic signaling family that has been implicated in pathogenesis of allergic airway diseases; however, the distinct function of individual Notch ligands remains elusive. We investigated whether Notch ligands, Jagged1 and DLL4, exert diffe
The approval of two messenger RNA (mRNA)-based COVID-19 vaccines have underscored the remarkable potential of RNA-based therapeutics [1,2,3]. Circular RNA (circRNA) is a covalently closed single-stranded RNA molecule [4, 5]. It is reported to present notable advantages over mRNA, including...
To investigate DLL3 localization, we performed immunofluorescence assays using H69, H524, SHP-77, BEAS-2B, and 16HBE cells. The cells were seeded into 24-well plates, fixed with 4% paraformaldehyde for 30 min, and then permeabilized with 0.4% Triton X-100 (Solarbio, IT9100) for 30 min....