(EP-NEN) using a standardized DLL3 IHC assay. DLL3 expression is enriched in SCLC, LCNEC along with combined histology lung cancers. Moreover, we find a wide range of DLL3 expression in high-grade EP-NEN. We describe heterogenous DLL3 expression not only in SCLC but also in different ...
Results showed that the maximum tolerated dose (MTD) was not reached in the overall population (n = 107), although 5 dose-limiting toxicities (DLTs) occurred––all reversible––including grade 3/4 cytokine release syndrome (CRS, n = 2), grade 3 confusional state (n = 1...