All three groups show that ric-8 mutants have several defects — asymmetric localization of cell-fate determinants is not maintained, mitotic spindles are misorientated and the sizes of the two daughter cells become almost equal. These observations indicate that RIC-8 is essential for proper ...
All wells were observed daily and after the first division of every primary cell (when two cells were evident in the well between days 1 and 7), one of the two daughter cells was transferred to a new plate prepared with a cytokine combination containing SFM plus IL3, IL6, GM-CSF and ...
During the emergence of neural crest cells from the neural tube, the expression of cadherins dynamically changes. In the embryo, the early neural tube expr... S Nakagawa,M Takeichi - 《Development》 被引量: 765发表: 1998年 The maternal sex determination gene daughterless has zygotic activity...
Mitosis- produces twoidenticaldaughter cells [有絲分裂:製造兩個相等的子細胞] - each daughter cell has the samekindandnumberof chromosomes as the original parent cell [每個子細胞都和原本的親代細胞有相同的染色體種類和數目] -interphase(resting stage) - chromosomes cannot be seen (it is in long &...
The asymmetric division ofDrosophilaneuroblasts involves the basal localization of cell fate determinants and the generation of an asymmetric, apicobasally oriented mitotic spindle that leads to the formation of two daughter cells of unequal size. These features are thought to be controlled by an api...
Programmed cell death – also known as apoptosis – is universal among higher organisms, and is a tightly regulated process that results in the disposal of damaged or unwanted cells. The latter variant is particularly important in the course of embryonic
A central question in developmental biology is how a single cell can divide to produce two progeny cells that adopt different fates. Different daughter cells can theoretically arise by uneven distribution of determinants upon cell division, i.e., due to intrinsic factors, or become different upon ...
of meiosis runs through the same five stages as discussed in mitosis.During the first round of division,two intermediate daughter cells are produced.By the end of the second round of meiotic division (meiosis II),the original diploid (2n) cell has become four haploid (n) daughter cells.Meiosi...
Meiosis in oocytes is demanding, requiring chromosomes to be evenly segregated between daughter cells while the cytoplasm should be unequally shared to benefit the oocyte. Indeed, oocytes are extremely large cells compared to most somatic cells and divid
Drosophila neuroblast asymmetric divisions generate two daughters of unequal size and fate. A complex of apically localized molecules mediates basal localization of cell fate determinants and apicobasal orientation of the mitotic spindle, but how daughter cell size is controlled remains unclear. Here we ...