Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan. Nat. Microbiol. https://doi.org/10.1038/s41564-019-0632-1 (2020). Su, H. N. et al. Structural visualization of septum formation in Staphylococcus warneri using ...
Nuclear trafficking pathways are regulated by an intracellular gradient of the small GTPase Ran, with a high concentration of RanGTP in the nucleus and high concentration of RanGDP in the cytoplasm. In addition to macromolecular trafficking, Nups also contribute to the control of gene expression, ...
Telophase rescue is regulated by TNF receptor-associated factor (DTRAF1), which binds to Baz and acts downstream of Egr/TNF56. Telophase rescue also depends on Worniu/Escargot/Snail family proteins and a microtubule-dependent Khc-73/Dlg pathway48,57. Pins did not form a protein complex with ...
31], which are anchored by Nup93 at the pore and are critical for NPC function [32]. Although Nup62 localizes to the centrosome during mitosis, little is known about the spatiotemporal localization and functions of Nup58 [33,34]. Depletion of Nup58 by RNA interference (RNAi) has been...
These observations will guide the development of improved strategies to benefit maternal and neonatal health in the country.The dynamics of global healthcare are demanding new skills and knowledge for nurses to address the evolving needs. Opportunities for developing crucial skills are presented through ...
Also, Arpc1b was found to be estrogen-regulated through estrogen receptor β (ERβ), not by androgen, in an ex vivo seminiferous tubule culture system [7]. In an attempt to understand the role played by molecular targets of estrogen during spermatogenesis, we have performed intratesticular ...
How the size of organs and tissues is regulated in development and regeneration is a fundamental question in biology [1, 2]. Fankhauser's historical observation of salamanders with a different ploidy demonstrated that cell numbers are inversely correlated with cell size and ploidy, allowing the org...
at PageID 225 (asserting a factual challenge that Plaintiffs named a member that would not be regulated under the statute). After careful, thorough, and extensive consideration of the complaint and briefing in support of, and in opposition to, the motion to dismiss, it is in the interest ...
(reliability measure). To verify the transcriptome data,lacZreporter fusions were constructed with the promoter of the upregulatedydcFGandsrfAAoperons, and the down-regulatedmtnKAoperon. The expression response of these fusions were in line with the transcriptome data (Fig. S8). Surprisingly, none...
One important open question is whether and how activity of the DENR·MCTS1 protein complex is regulated. MCTS1 can be phosphorylated by Cdc2 on Ser118 and by MAPK on Thr81, the later of the two leading to stabilization of MCTS1 protein43. Whether other post-translational modifications affect...