Understanding the molecular and cellular processes involved in lung epithelial regeneration may fuel the development of therapeutic approaches for lung diseases. We combine mouse models allowing diphtheria toxin-mediated damage of specific epithelial cell types and parallel GFP-labeling of functionally dividing...
This article explores the ways in which having a rare skin disease (pemphigus) can reveal and redefine individuals' interpersonal relationships and how they experience and use the support of loved ones. It examines two aspects of "care": emotional support and practical support (through the ...
Respiratory diseases are among the leading causes of death worldwide1. In the adult lung, epithelial cells possess a low steady-state turnover but can respond to lung injury with proliferation and differentiation to replace damaged cells2. Understanding the process of lung regeneration at the cellul...
This paper is mainly based on qualitative interviews, archival research, and the analysis of socioeconomic statistics and legislation. The case study of Quintero-Puchuncaví is grounded on a six-month fieldwork in Chile, which featured 30 semi-structured interviews with former and current industrial ...
Infrastructure for the Kim Laboratory was provided by a John Evans Leadership Fund grant from the Canadian Foundation for Innovation and the Ontario Innovation Trust. This work was supported by operating grants from the Canadian Institutes of Health Research (PJT#156196) to P.K.K.; M.B is a ...
This of course only provides the “Northern” perspective on these partnerships and how they apply to the framework used. Results The international projects, both development and research, within the DTHM can be divided into four categories: Human resource and institutional development; Humanitarian ...
Innovation remains the key driver of success. New wins in all business segments could only be achieved thanks to the recognition of our customers of Givaudan's innovation capabilities. In 2005, Givaudan fragrances introduced another four new proprietary molecules, developed in the basic research ...
While the researchers are glad to have found an answer to some of the questions regarding cell division, there are still many more to be answered and further research must be conducted in order to ascertain the answers to these lingering questions. In the meantime, the researchers are on the...
Our findings support a model where the ER recruits lysosomes to act in concert at the fission site for the efficient division of mitochondria. 1 Cell Biology Program, Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada. 2 Department of Biochemistry, ...
This review aims to present an overview of the symmetrical and asymmetric divisions of SCs in aged muscle as basic mechanisms behind SC fate and balance between self-renewal and differentiation and highlight the latest research data in the field. The better we understand this phenomenon, the more...