In the data analyzed here, there was not substantial evidence of pulsing, but this does not mean it might not be predictive in other contexts. Based on a systematic model interpretation algorithm, our results suggested that no single time point in the ERK and Akt time courses was solely more...
There is evidence that the cell wall is made of helical PG ropes connected by peptide chains.30 The overall impression of the cell is that of a carefully tuned pressure vessel. Sign in to download full-size image Figure 1. Bacterial physiology. The cell is contained within a living ...
As far as we know, there is little experimental evidence supporting the distinct fate of stem cells after implantation of scaffolds during the regeneration of defective bone. Our present repair strategy merely aims to explore the potential in self-renewal and osteo-differentiation of stem cells isola...
This is a consensus document providing recommendations based on expert opinion and best available evidence, regarding the optimal conditions for the safe practice of pediatric neuroradiology. Article 1: definition Pediatric neuroradiology is a subspecialty within the greater radiologic field, with possible ...
During radiologic or nuclear accidents, high-dose ionizing radiation (IR) can cause gastrointestinal syndrome (GIS), a deadly disorder that urgently needs effective therapy. Unfortunately, current treatments based on natural products and antioxidants hav
Evidence for a dual role of PBP1 in the cell division and cell separation of Staphylococcus aureus. Mol. Microbiol. 72, 895–904 (2009). Article CAS PubMed PubMed Central Google Scholar Pinho, M. G., Filipe, S. R., de Lencastre, H. & Tomasz, A. Complementation of the essential ...
Accumulated genetic mutations and changes of bone marrow (BM) microenvironment/niche signals are critical for leukemogenesis and resistance to conventional treatments (Corces-Zimmerman and Majeti, 2014, Greim et al., 2014). Increasing evidence has implied that reprogrammed metabolic alterations may be ...
This process begins when the Secretary issues an initial price offer to the manufacturer based upon several factors including, inter alia, evidence about alternative treatments. Doc. No. 1 at PageID 20; 42 U.S.C. §§ 1320f-3(b)(2)(B), 1320f-3(e)(1)-(2). The manufacturer must ...
has produced compelling evidence that just particular parts of cell cycle control must be compromised for cancer cells to continue to proliferate. According to this research, the most relevant phase that needs to be altered for cancer cells to continue their uncontrolled division is their capacity to...
Exogenous Cyclin E or proteasome inhibitor administered to the developing ASPM null cortex rescue its NPC aberrant CC timing and fate determination, but not the abnormal mitotic cleavage orientation, providing conclusive evidence linking the mode of progenitor division to the time residing within the ...