C Case example of a bivalent LOCK at a TAD boundary in H1-hESC cells on the chromosome 16q22.1 locus. The ChIP-seq signal intensities for H3K4me1, H3K27me3 and regulators of chromatin interactions are shown. D Comparison of the median of H3K4me1, H3K27me3 and H3K9me3 ChIP-seq ...
9]. In all species studied so far, accessory chromosomes are distinguished from core chromosomes by their high repeat content and low gene density as shown by chromosome staining and biochemical methods [2,10]. Currently, no studies on the chromatin structure of accessory chromosomes in fungi are...
In female mammals, one of the two X chromosomes is inactivated to compensate for the difference in dosage of X-linked genes between males and females. X inactivation involves sequential alterations to the chromatin that ultimately lead to the transcriptional repression of genes on the X chromosome....
Background: The morphologic distinction between thymic carcinomas and thymomas, specifically types B3, A, and occasionally micronodular thymomas with lymphoid stroma (MNTLS) can be challenging, as has also been shown in interobserver reproducibility studies. Since thymic carcinomas have a worse progn...