InvalidOperationException: The LINQ expression 'ProjectionBindingExpression: 0' could not be translated. Either rewrite the query in a form that can be translated, or switch to client evaluation explicitly by inserting a call to 'AsEnumerable', 'AsAsyncEnumerable', 'ToList', or 'ToListAsync'. ...
Thus, even though we could not determine whether the oxidation was aerobic or anaerobic, a major portion of CH4 was oxidized in suboxic hypolimnion. Several OTUs annotated as OD1, such as OTU28, OTU1237 and OTU1357, were highly abundant in these depth horizons and as mentioned above ...
If the heterodimer has a weaker repulsive output than a Robo homodimer, then this could explain the decrease in midline repulsion at low increased levels of Robo2. However, Robo2 does not just interfere with midline repulsion; it can also mediate it. Higher levels of ectopic Robo2 lead to ...
Biotinylated-peptides, designed around sequences in the SDS1 and SDS2 regions of the Neh6 domain in mouse Nrf2, were coupled with Streptavidin, which had first been immobilized on agarose beads, and used in pull-down assays to identify those that could bind to in vitro translated [35S]...
Transcripts of pseudogenes that do not contain disabling mutations in the CDS could produce CaM-like proteins if they are correctly transcribed and translated and therefore could potentially exert diverse functional roles. Indeed, a functional intronless CaM-like gene in human has been found [52,60...
could not easily be distinguished at the scale with individual arrows. In all cases, only one DNA strand is shown and directionality can be inferred from the direction of TSS arrows. The scale is given between the genome and the MAPP profile and is zeroed at the translation start site of ...
We’re sorry, something doesn't seem to be working properly. Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.Abstract Background Despite recent studies on the role of ubiquitin-related SUMO modifier in cell fate decisions, our underst...
Many factors could contribute to the effectiveness of miRNA-mediated mRNA translational suppression when the target sites are relocated into different regions of the genome or mRNA (Bartel, 2009, Fang and Rajewsky, 2011, Lin and Ganem, 2011, Pasquinelli, 2012). miRNA-target sequence accessibility ...
Although recombinant tBid could still target Vdac2 À / À mitochondria (Figure 2e), the resident Bak could not mediate cytochrome c release (Figure 2e) even in response to high doses of tBid (Figure 2f). Nor could resident Bak mediate cytochrome c release induced by high dose (10 ...
In fact, previous genotype-phenotype studies of MPZ mutations could not explain the mild phenotype asso- ciated with dominant-negative truncated proteins26,37,38. Invoking NMD not only delineates the genotype-phenotype correlation for truncating mutations, but it also facilitates a functional analysis...