Soluble effervescent tablets get dissolved quickly when put in water to give a solution which can be easily consumed by patients with temporarily warding off drowsiness and restoring alertness. The present investigation describes the formulation methodology, evaluation parameters and futur...
adults and children 12 years of age and over: take 1 to 2 (25 to 50 mg) tablets once daily, or as directed by a physician. Other information ■ store at 20-30°C (68-86°F) Inactive ingredients acesulfame potassium, erythritol, hydroxypropyl cellulose, colloidal silicon dioxide, mannitol...
In the present work, mouth dissolving tablets of losartan potassium were design with a view to enhance the patient compliance and provide a quick onset of action. Losartan potassium is an angiotensin receptor antagonist, used in the management of hypertension. It has low bioavailability due to its...
In-vitroDissolution Studies of Febuxostat Tablets:Dissolution studies were carried on Febuxostat tablets using the U.S.P paddle method (apparatus II) with 0.05 M phosphate buffer pH 6.0 as dissolution medium by maintaining the bath ...
(1 × 1 cm) were measured in 3 mL of artificial saliva prepared as previously described: 14.4 mM sodium chloride, 16.1 mM mg potassium chloride, 1.31 mM calcium chloride dihydrate, 0.54 mM magnesium chloride hexahydrate, 1.96 mM dibasic potassium phosphate adjusted to pH 5.7 ± 0.01 ...
For the determination of surface pH, three films of each formulation were allowed to contact with 1 mL of distilled water for 1 hour at room temperature and measured by pH meter (Jenway, Staffordshire, UK). The surface pH was mea- sured by bringing the electrode in contact with the ...
The aqueous phase was prepared by blending potassium sorbate, ethylenediaminetetra acetic acid (EDTA), citric acid and salt in the water in an aqueous phase tank or in a stainless steel container. While stirring the oil phase at high speed, about 800 rpm, the aqueous phase was poured slowly...
The water soluble sugars which can be used in the process according to the present invention are Mannitol, Sorbitol, Xylitol and/or the like. The non-sugar sweeteners which can be used in the process according to the present invention are Aspartame, Acesulfame potassium, Saccharin sodium, Cyclama...
Samples were mixed with potassium bromide (spectroscopic grade) and compressed into disks using hydraulic press before scanning from 4,000 to 600 cm-1. Differential scanning calorimetry Differential scanning calorimetry (DSC) scans were recorded for the selected niosomal film, its corresponding physical...
The present invention relates to processes for the preparation of tablets which dissolve rapidly in the mouth and provide an excellent mouthfeel. The tablets of the invention comprise a compound which