The molecular regulation of human hematopoietic stem cell (HSC) maintenance is therapeutically important, but limitations in experimental systems and interspecies variation have constrained our knowledge of this process. Here, we have studied a rare genetic disorder due toMECOMhaploinsufficiency, characterized...
Slam Jam, Ill-Studio and General_Index present the Attention Deficit Disorder Prosthetic Memory Program. A perspective on the cultural and cognitive flattening of human networked recollections through a series of encyclopedic explorations.
If the meme about only using 10 percent of our brains were true, would using 100 percent of our brain logically result in a stroke of genius? Probably not. To investigate how cells in the brain light up in response to learning, a group led by Takaki Komiyama used a similar imaging techn...
Enthusiasm for life tends to wane when we lackenergy. Example: In response to, “We are going to walk our dog, it’s a lovely day, do come with us.” what might a reply of, “Not today” mean. If the only reason for not walking is a lack ofenergythat person needs help. ...
Reverse transcription was performed using the SuperScript IV First-Strand Synthesis System (ThermoFisher Scientific) with random hexamers. cDNA was then used together with a custom TaqMan probe (Supplementary Table1), which spans the back-splice junction of circCCNT2, and TaqMan Universal PCR Master...
Whilst metrics may capture some partial dimensions of research ‘impact’, theycannot be used as any kind of proxy for measuring research ‘quality’. Not only is thereno logical connectionbetween citation counts and the quality of academic research, but the adoption of such a system couldsystemat...
when telling Erika about the powerful final clubs and the importance of belonging to one them, he clearly aches to be part of that system, not a member of Alpha Epsilon Pi, the Jewish fraternity. When Eduardo receives an invitation to be “punched” by the Phoenix Club, a prestigious...
I felt betrayal. I’d devoted myself to a system that promised being skinny would mean eradicating pain, living on a beach, watching men kill each other to be my boyfriend, and instead the system eradicated all life other than pain. But if contentment hadn’t found me back when I still...
is a US-style expansion based onprecarity,a prestige elite, and debt bubbles. Some at the top are already breaking from the national pay spine, inaugurating a two-tier system. Consider this trend alongside the state of university finances. What is it to look at this and say things aren’...
I felt betrayal. I’d devoted myself to a system that promised being skinny would mean eradicating pain, living on a beach, watching men kill each other to be my boyfriend, and instead the system eradicated all life other than pain. But if contentment hadn’t found me back when I still...