H., van der Hoven, J., Harasta, A., Bi, M., Ittner, A., et al. (2016). Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia. Neurosci. Lett. 631, 24-29. doi: 10.1016/j. neulet.2016.08.007...
摘要: Frontotemporal dementia (FTD) presents clinically with behavioral changes including disinhibition. Mutations in the tau-encoding MAPT关键词: Frontotemporal dementia Tau Transgenic mouse model Behavior DOI: 10.1016/j.neulet.2016.08.007 被引量: 9 ...
In mutant mice, this behavior has been associated with either enhanced (Parks et al, 1998) or reduced anxiety-like behavior (Bale and Vale, 2003; Tschenett et al, 2003). Our present findings help define the conceptual framework for the interpretation of the stress response exhibited by MAO ...
lines of behavior, which often involves obeying authorities (like the experimenter who is requesting accurate judgments about the stimulus lines), while the disinhibition track involves greater conformity to the behavior of peers (like the confederates who are giving wrong answers to the perception ...
Rislenemdaz treatment in the lateral habenula improves despair-like behavior in mice Article 08 March 2020 Dl-3-n-butylphthalide attenuates mouse behavioral deficits to chronic social defeat stress by regulating energy metabolism via AKT/CREB signaling pathway Article Open access 03 February 2020 ...
Alcohol and the ability to inhibit behavior in men and women. J Stud Alcohol. 1997;58:600–5. PubMed CAS Google Scholar Marczinski CA, Fillmore MT. Pre-response cues reduce the impairing effects of alcohol on the execution and suppression of responses. Exp Clin Psychopharmacol. 2003;11:...
Behavioural disinhibition implies the loss of restraint over some form of social behaviour. Such disinhibition can be drug induced and, on rare occasions, lead to extreme acts of aggression or violence. Examples of behavioural disinhibition are often considered paradoxical and rare reactions to drugs,...
Here we tested the hypothesis that sustained enhancement of GABAergic transmission alone is sufficient to elicit antidepressant-like behavior, using disinhibition of GABAergic interneurons. We focused on somatostatin-positive (SST) GABAergic interneurons because of evidence that their function is compromised...
G Ambar,S Chiavegatto - 《Genes Brain & Behavior》 被引量: 74发表: 2009年 Anabolic-androgenic steroid treatment induces behavioral disinhibition and downregulation of serotonin receptor messenger RNA in the prefrontal cortex and amygdala of male mice. 2009. Anabolic-androgenic steroid treatment induces...
A. Chronic unpredictable stress induces a cognitive deficit and anxiety-like behavior in rats that is prevented by chronic antidepressant drug treatment. Neuropsychopharmacology 33, 320–331 (2008). Article CAS PubMed Google Scholar McEwen, B. S., Eiland, L., Hunter, R. G. & Miller, M. ...